| Literature DB >> 15490325 |
Alessandra Braca1, Giuseppina Autore, Francesco De Simone, Stefania Marzocco, Ivano Morelli, Fabio Venturella, Nunziatina De Tommasi.
Abstract
Eight new oleanane and lupane saponins (1-8) as well as two new benzyl glycosides (9 and 10) were isolated from the aerial parts of Schefflera rotundifolia (Ten) Frodin (Araliaceae) together with two known benzyl glycosides. Their structures were established using 1D- and 2D-NMR spectroscopy and mass spectrometry. The antiproliferative activity of all compounds was evaluated using three continuous murine and human culture cell lines J774.A1, HEK-293, and WEHI-164. Compounds 7 and 8, having betulinic acid as aglycone, were the most active constituents.Entities:
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Year: 2004 PMID： 15490325 DOI： 10.1055/s-2004-832623
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352