OBJECTIVE: Antioxidant enzymes status was investigated in children with acute otitis media (AOM) and acute tonsillitis. The aim was to determine the effect of oxidative damage due to free radicals on the antioxidant enzymes status in children with AOM and acute tonsillitis. METHODS: We measured erythrocyte levels of superoxide dismutase and glutathione peroxidase (GPx) and activity of serum catalase, ceruloplasmin, albumin and total bilirubin in 23 children with AOM, 27 with acute tonsillitis and 17 control subjects. RESULTS: There was statistically significant difference between the groups for all parameters. All antioxidant activities except for albumin level were increased in the studies groups. When the values of AOM and acute tonsillitis were compared, there was statistically significant difference between the groups for erythrocyte GPx. CONCLUSION: Our findings indicate that not only a few antioxidant enzymes but almost all antioxidant activities showed a significant enhancement in children with AOM and acute tonsillitis.
OBJECTIVE: Antioxidant enzymes status was investigated in children with acute otitis media (AOM) and acute tonsillitis. The aim was to determine the effect of oxidative damage due to free radicals on the antioxidant enzymes status in children with AOM and acute tonsillitis. METHODS: We measured erythrocyte levels of superoxide dismutase and glutathione peroxidase (GPx) and activity of serum catalase, ceruloplasmin, albumin and total bilirubin in 23 children with AOM, 27 with acute tonsillitis and 17 control subjects. RESULTS: There was statistically significant difference between the groups for all parameters. All antioxidant activities except for albumin level were increased in the studies groups. When the values of AOM and acute tonsillitis were compared, there was statistically significant difference between the groups for erythrocyte GPx. CONCLUSION: Our findings indicate that not only a few antioxidant enzymes but almost all antioxidant activities showed a significant enhancement in children with AOM and acute tonsillitis.
Authors: Mustafa Cemek; Mehmet Emin Büyükokuroğlu; Ahmet Büyükben; Fatih Aymelek; Fatma Yilmaz; Murat Doğan; Fatih Sanli; Abdurrahman Uner; Derya Yildirim Journal: Pediatr Cardiol Date: 2010-07-01 Impact factor: 1.655
Authors: Filiz Aydoğan; Eren Taştan; Emine Aydın; Mehmet Senes; Sükran Akgedik; Rukiye Berkem; Ahmet Tekeli; Aylin Haklıgör; Hüseyin Ustün Journal: Indian J Otolaryngol Head Neck Surg Date: 2012-01-06
Authors: Filiz Aydogan; Emine Aydin; Eren Tastan; Necmi Arslan; Mehmet Senes; Ilhan Unlu; Ali Kavuzlu Journal: Indian J Otolaryngol Head Neck Surg Date: 2012-08-21
Authors: Jane Schmitz; Keith P West; Subarna K Khatry; Lee Wu; Steven C Leclerq; Sureswor L Karna; Joanne Katz; Alfred Sommer; Joseph Pillion Journal: BMJ Date: 2012-01-10