Literature DB >> 15486457

Synthesis of the Lewis b hexasaccharide and HSA-conjugates thereof.

Martina Lahmann1, Linnéa Bülow, Peter Teodorovic, Helena Gybäck, Stefan Oscarson.   

Abstract

An efficient and short route has been elaborated for the aminopropyl spacer equipped Leb hexasaccharide. For the preparation of HSA-conjugates of this oligosaccharide, the use of disuccinimidyl suberate (DSS) and disuccinimidyl glutarate (DSG) as cross-linker reagents has been evaluated. This conjugation method emerged as being faster and easier to monitor by standard MALDI-TOF spectrometry than squarate ester based conjugations of similar efficiency if DSS is used as cross-linker.

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Year:  2004        PMID： 15486457     DOI： 10.1023/B:GLYC.0000045097.19353.73

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  7 in total

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Authors:  A V Demchenko; G J Boons
Journal:  J Org Chem       Date:  2001-04-20       Impact factor: 4.354

2.  Conjugating oligosaccharides to proteins by squaric acid diester chemistry: rapid monitoring of the progress of conjugation, and recovery of the unused ligand.

Authors:  A Chernyak; A Karavanov; Y Ogawa; P Kovác
Journal:  Carbohydr Res       Date:  2001-02-28       Impact factor: 2.104

3.  Synthesis of the Lewis b hexasaccharide and squarate acid-HSA conjugates thereof with various saccharide loadings.

Authors:  A Chernyak; S Oscarson; D Turek
Journal:  Carbohydr Res       Date:  2000-11-03       Impact factor: 2.104

4.  Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging.

Authors:  D Ilver; A Arnqvist; J Ogren; I M Frick; D Kersulyte; E T Incecik; D E Berg; A Covacci; L Engstrand; T Borén
Journal:  Science       Date:  1998-01-16       Impact factor: 47.728

5.  Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens.

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6.  Synthesis of a tri- and a hepta-saccharide which contain alpha-L-fucopyranosyl groups and are part of the complex type of carbohydrate moiety of glycoproteins.

Authors:  H Lönn
Journal:  Carbohydr Res       Date:  1985-06-15       Impact factor: 2.104

7.  Carbohydrate carriers affect adhesion of H. pylori to immobilized Leb-oligosaccharide.

Authors:  Naoya Kojima; Keita Seino; Yoshia Sato; Tsuguo Mizuochi
Journal:  FEBS Lett       Date:  2002-04-24       Impact factor: 4.124
  7 in total
  4 in total

1.  Syntheses of Lewis(x) and dimeric Lewis(x): construction of branched oligosaccharides by a combination of preactivation and reactivity based chemoselective one-pot glycosylations.

Authors:  Adeline Miermont; Youlin Zeng; Yuqing Jing; Xin-shan Ye; Xuefei Huang
Journal:  J Org Chem       Date:  2007-10-16       Impact factor: 4.354

Review 2.  Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004.

Authors:  David J Harvey
Journal:  Mass Spectrom Rev       Date:  2009 Mar-Apr       Impact factor: 10.946

3.  Synthesis of 6-PEtN-α-D-GalpNAc-(1->6)-β-D-Galp-(1->4)-β-D-GlcpNAc-(1->3)-β-D-Galp-(1->4)-β-D-Glcp, a Haemophilus influenzae lipopolysacharide structure, and biotin and protein conjugates thereof.

Authors:  Andreas Sundgren; Martina Lahmann; Stefan Oscarson
Journal:  Beilstein J Org Chem       Date:  2010-07-26       Impact factor: 2.883

4.  Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of Helicobacter pylori.

Authors:  Mark Reihill; Lorenzo Guazzelli; Han Remaut; Stefan Oscarson
Journal:  Molecules       Date:  2020-09-18       Impact factor: 4.411
  4 in total

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