| Literature DB >> 15485624 |
Jagan R Muppidi1, Jürg Tschopp, Richard M Siegel.
Abstract
Signaling by receptors in the TNF receptor (TNFR) superfamily mediate biological outcomes ranging from inflammation to apoptosis and other forms of programmed cell death. How receptor signaling mediates these divergent responses is just beginning to be understood. Here, we discuss how receptor submembrane localization and the formation of alternate signaling complexes can alter the fate of cells stimulated through TNFRs with a death domain, also known as "death receptors."Entities:
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Year: 2004 PMID： 15485624 DOI： 10.1016/j.immuni.2004.10.001
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745