Literature DB >> 15485622

Id3 knockout mice as a new model for sjogren's syndrome: only a T cell defect or more?

Marjan A Versnel1.   

Abstract

Id3(-/-) mice were found to have autoantibodies, lymphocytic infiltrates in, and decreased secretion by exocrine glands. Similar symptoms are found in primary Sjogren's Syndrome. In this issue of Immunity, Li and colleagues suggest an important role for Id3 function in T cell development and Sjogren's Syndrome.

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Year:  2004        PMID： 15485622     DOI： 10.1016/j.immuni.2004.10.003

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  3 in total

1.  UVB upregulates the bax promoter in immortalized human keratinocytes via ROS induction of Id3.

Authors:  Valerie Anne Trabosh; Ahmad Daher; Kyle A Divito; Karishma Amin; Cynthia M Simbulan-Rosenthal; Dean S Rosenthal
Journal:  Exp Dermatol       Date:  2008-10-23       Impact factor: 3.960

2.  Aquaporin gene therapy corrects Sjögren's syndrome phenotype in mice.

Authors:  Zhennan Lai; Hongen Yin; Javier Cabrera-Pérez; Maria C Guimaro; Sandra Afione; Drew G Michael; Patricia Glenton; Ankur Patel; William D Swaim; Changyu Zheng; Cuong Q Nguyen; Fred Nyberg; John A Chiorini
Journal:  Proc Natl Acad Sci U S A       Date:  2016-05-02       Impact factor: 11.205

3.  Smad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse.

Authors:  Donghee Kim; Jae Young Kim; Hee-Sook Jun
Journal:  Oncotarget       Date:  2016-12-06
  3 in total

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