Literature DB >> 15485334

Rickettsial vaccines: the old and the new.

Allen L Richards1.   

Abstract

In the past century vaccine development for prevention of rickettsial diseases has been prolific. However, in the past 20 years no new rickettsial vaccine has been manufactured and there are currently no new or old rickettsial vaccines licensed. Early rickettsial vaccines were difficult, expensive and very hazardous to produce. Molecular biology techniques of today are currently being used to develop new rickettsial vaccines that are standardized, inexpensive, nonhazardous and efficacious.

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Year:  2004        PMID： 15485334     DOI： 10.1586/14760584.3.5.541

Source DB:  PubMed          Journal:  Expert Rev Vaccines        ISSN： 1476-0584            Impact factor:   5.217


  8 in total

Review 1.  Emerging and threatening vector-borne zoonoses in the world and in Europe: a brief update.

Authors:  Eva Jánová
Journal:  Pathog Glob Health       Date:  2019-03-27       Impact factor: 2.894

2.  Multispacer typing of Rickettsia prowazekii enabling epidemiological studies of epidemic typhus.

Authors:  Yong Zhu; Pierre-Edouard Fournier; Hiroyuki Ogata; Didier Raoult
Journal:  J Clin Microbiol       Date:  2005-09       Impact factor: 5.948

3.  The beginning of an era of functional genomics in Rickettsiology is steeped in history.

Authors:  Ulrike G Munderloh
Journal:  Proc Natl Acad Sci U S A       Date:  2019-09-17       Impact factor: 11.205

4.  Detection of antibodies against Orientia tsutsugamushi Sca proteins in scrub typhus patients and genetic variation of sca genes of different strains.

Authors:  Na-Young Ha; Yuri Kim; Ji-Hye Choi; Myung-Sik Choi; Ik-Sang Kim; Yeon-Sook Kim; Nam-Hyuk Cho
Journal:  Clin Vaccine Immunol       Date:  2012-07-11

5.  The lspA gene, encoding the type II signal peptidase of Rickettsia typhi: transcriptional and functional analysis.

Authors:  M Sayeedur Rahman; Shane M Ceraul; Sheila M Dreher-Lesnick; Magda S Beier; Abdu F Azad
Journal:  J Bacteriol       Date:  2006-11-10       Impact factor: 3.490

Review 6.  Technical transformation of biodefense vaccines.

Authors:  Shan Lu; Shixia Wang
Journal:  Vaccine       Date:  2009-11-05       Impact factor: 3.641

7.  Phenotypic characterization of peripheral T cells and their dynamics in scrub typhus patients.

Authors:  Bon-A Cho; Youngho Ko; Yeon-Sook Kim; Sanguk Kim; Myung-Sik Choi; Ik-Sang Kim; Hang-Rae Kim; Nam-Hyuk Cho
Journal:  PLoS Negl Trop Dis       Date:  2012-08-14

8.  Rickettsia parkeri with a Genetically Disrupted Phage Integrase Gene Exhibits Attenuated Virulence and Induces Protective Immunity against Fatal Rickettsioses in Mice.

Authors:  Esteban Arroyave; Ilirjana Hyseni; Nicole Burkhardt; Yong-Fang Kuo; Tian Wang; Ulrike Munderloh; Rong Fang
Journal:  Pathogens       Date:  2021-06-30
  8 in total

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