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Literature DB >> 15485135

The stroke-prone spontaneously hypertensive rat: how good is it as a model for cerebrovascular diseases?

Toru Nabika¹, ZongHu Cui, Junichi Masuda.

Abstract

1. Cerebrovascular diseases (CVDs) in humans are a mixture of diseases with different etiologies. 2. Although the stroke-prone spontaneously hypertensive rat (SHRSP) cannot represent all types of CVDs, it is probably a good genetic model for particular types such as lacunar infarction and intracerebral hemorrhage. 3. Genetic studies suggested that SHRSP has genetic susceptibility to stroke independent of its severe hypertension. Studies on SHRSP may provide useful information with which to dissect genetic susceptibility to particular types of CVDs.

Entities: Disease Species

Mesh：

Year: 2004 PMID： 15485135 DOI： 10.1023/b:cemn.0000036402.79129.2f

Source DB: PubMed Journal: Cell Mol Neurobiol ISSN： 0272-4340 Impact factor: 5.046

20 in total

1. Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease.

Authors: S Rubattu; M Volpe; R Kreutz; U Ganten; D Ganten; K Lindpaintner
Journal: Nat Genet Date: 1996-08 Impact factor: 38.330

2. Impaired blood-brain barrier function in angiotensinogen-deficient mice.

Authors: Y Kakinuma; H Hama; F Sugiyama; K Yagami; K Goto; K Murakami; A Fukamizu
Journal: Nat Med Date: 1998-09 Impact factor: 53.440

3. Alterations of the blood-brain barrier and glial cells in white-matter lesions in cerebrovascular and Alzheimer's disease patients.

Authors: H Tomimoto; I Akiguchi; T Suenaga; M Nishimura; H Wakita; S Nakamura; J Kimura
Journal: Stroke Date: 1996-11 Impact factor: 7.914

4. Increased transendothelial channel transport of cerebral capillary endothelium in stroke-prone SHR.

Authors: M Tagami; A Kubota; T Sunaga; H Fujino; H Maezawa; M Kihara; Y Nara; Y Yamori
Journal: Stroke Date: 1983 Jul-Aug Impact factor: 7.914

5. Photothrombotic middle cerebral artery occlusion in spontaneously hypertensive rats: influence of substrain, gender, and distal middle cerebral artery patterns on infarct size.

Authors: H Cai; H Yao; S Ibayashi; H Uchimura; M Fujishima
Journal: Stroke Date: 1998-09 Impact factor: 7.914

6. Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium.

Authors: S Kerr; M J Brosnan; M McIntyre; J L Reid; A F Dominiczak; C A Hamilton
Journal: Hypertension Date: 1999-06 Impact factor: 10.190

7. The region responsible for stroke on chromosome 4 in the stroke-prone spontaneously hypertensive rat.

Authors: K Ikeda; Y Nara; C Matumoto; T Mashimo; T Tamada; M Sawamura; T Nabika; Y Yamori
Journal: Biochem Biophys Res Commun Date: 1996-12-13 Impact factor: 3.575

8. Two-kidney, two clip renovascular hypertensive rats can be used as stroke-prone rats.

Authors: J Zeng; Y Zhang; J Mo; Z Su; R Huang
Journal: Stroke Date: 1998-08 Impact factor: 7.914

9. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone.

Authors: S Rajagopalan; S Kurz; T Münzel; M Tarpey; B A Freeman; K K Griendling; D G Harrison
Journal: J Clin Invest Date: 1996-04-15 Impact factor: 14.808

10. Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus.

Authors: B Jeffs; J S Clark; N H Anderson; J Gratton; M J Brosnan; D Gauguier; J L Reid; I M Macrae; A F Dominiczak
Journal: Nat Genet Date: 1997-08 Impact factor: 38.330

19 in total

Review 1. Sexual dimorphism in ischemic stroke: lessons from the laboratory.

Authors: Bharti Manwani; Louise D McCullough
Journal: Womens Health (Lond) Date: 2011-05

2. Mycophenolate mofetil prevents cerebrovascular injury in stroke-prone spontaneously hypertensive rats.

Authors: Isha S Dhande; Yaming Zhu; Michael C Braun; M John Hicks; Scott E Wenderfer; Peter A Doris
Journal: Physiol Genomics Date: 2016-12-23 Impact factor: 3.107

3. Regional cerebral blood flow and arterial blood volume and their reactivity to hypercapnia in hypertensive and normotensive rats.

Authors: Tae Kim; J Richard Jennings; Seong-Gi Kim
Journal: J Cereb Blood Flow Metab Date: 2013-11-20 Impact factor: 6.200

4. Blood pressure-independent factors determine the susceptibility to delayed neuronal death in the stroke-prone spontaneously hypertensive rats.

Authors: Yasuko Sakurai-Yamashita; Toru Nabika; Masami Niwa
Journal: Cell Mol Neurobiol Date: 2010-03 Impact factor: 5.046

5. Quantitative analysis of delayed neuronal death in the hippocampal subfields of SHRSP and SHR.

Authors: Mitsuhiro Daisu; Toshihisa Hatta; Yasuko Sakurai-Yamashita; Toru Nabika; Kouzo Moritake
Journal: Cell Mol Neurobiol Date: 2009-01-27 Impact factor: 5.046

6. Spontaneous white matter lesion in brain of stroke-prone renovascular hypertensive rats: a study from MRI, pathology and behavior.

Authors: Yuhua Fan; Linfang Lan; Lu Zheng; Xiaotan Ji; Jing Lin; Jinsheng Zeng; Ruxun Huang; Jian Sun
Journal: Metab Brain Dis Date: 2015-09-19 Impact factor: 3.584

Review 10. Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes.

Authors: Adviye Ergul; Sherif Hafez; Abdelrahman Fouda; Susan C Fagan
Journal: Transl Stroke Res Date: 2016-03-30 Impact factor: 6.829