AIM: To assess Helicobacter pylori (H pylori) seroprevalence in a cohort of Greek patients with lung cancer. METHODS: Seventy-two lung cancer patients (55 males and 17 females, aged 58.2+/-11.7 years) and 68, age and gender-matched, control subjects were enrolled. All subjects underwent an enzyme-linked immunosorbent assay IgG serologic test for H pylori diagnosis. RESULTS: A correlation between age and H pylori IgG level was detected for both lung cancer patients (r = 0.42, P = 0.004) and controls (r = 0.44, P = 0.004). Seropositivity for H pylori did not differ significantly between patients with lung cancer and controls (61.1% vs 55.9%, P>0.05). Concerning the mean serum concentration of IgG antibodies against H pylori, no significant difference between the two groups was detected (32.6+/-19.1 vs 27.4+/-18.3 U/mL, P>0.05). CONCLUSION: No significant association between H pylori infection and lung cancer was found.
AIM: To assess Helicobacter pylori (H pylori) seroprevalence in a cohort of Greek patients with lung cancer. METHODS: Seventy-two lung cancerpatients (55 males and 17 females, aged 58.2+/-11.7 years) and 68, age and gender-matched, control subjects were enrolled. All subjects underwent an enzyme-linked immunosorbent assay IgG serologic test for H pylori diagnosis. RESULTS: A correlation between age and H pylori IgG level was detected for both lung cancerpatients (r = 0.42, P = 0.004) and controls (r = 0.44, P = 0.004). Seropositivity for H pylori did not differ significantly between patients with lung cancer and controls (61.1% vs 55.9%, P>0.05). Concerning the mean serum concentration of IgG antibodies against H pylori, no significant difference between the two groups was detected (32.6+/-19.1 vs 27.4+/-18.3 U/mL, P>0.05). CONCLUSION: No significant association between H pylori infection and lung cancer was found.
Authors: A Ogihara; S Kikuchi; A Hasegawa; M Kurosawa; K Miki; E Kaneko; H Mizukoshi Journal: J Gastroenterol Hepatol Date: 2000-03 Impact factor: 4.029
Authors: K W Tsang; S K Lam; W K Lam; J Karlberg; B C Wong; W H Hu; W W Yew; M S Ip Journal: Am J Respir Crit Care Med Date: 1998-10 Impact factor: 21.405
Authors: Jill Koshiol; Roberto Flores; Tram K Lam; Philip R Taylor; Stephanie J Weinstein; Jarmo Virtamo; Demetrius Albanes; Guillermo Perez-Perez; Neil E Caporaso; Martin J Blaser Journal: PLoS One Date: 2012-02-24 Impact factor: 3.240