Literature DB >> 15484196

Illuminating zinc in biological systems.

Nathaniel C Lim1, Hedley C Freake, Christian Brückner.   

Abstract

Zinc is the second most abundant transition metal in the human body, fulfilling a multitude of biological roles, but the mechanisms underlying its physiology are poorly understood. The lack of knowledge is, in part, due to the hitherto limited techniques available to track zinc in biological systems. The recent emergence of a number of zinc-specific molecular sensors has provided a new tool to image zinc in live cells and tissue samples. This contribution highlights the concepts behind using zinc-specific fluorescent molecular sensors to gain information about zinc action in biological samples, and provides representative examples of images recorded.

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Year:  2004        PMID： 15484196     DOI： 10.1002/chem.200400599

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  29 in total

1.  A selective turn-on fluorescent sensor for imaging copper in living cells.

Authors:  Li Zeng; Evan W Miller; Arnd Pralle; Ehud Y Isacoff; Christopher J Chang
Journal:  J Am Chem Soc       Date:  2006-01-11       Impact factor: 15.419

2.  Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry.

Authors:  Elizabeth M Nolan; Stephen J Lippard
Journal:  Acc Chem Res       Date:  2009-01-20       Impact factor: 22.384

Review 3.  In situ imaging of metals in cells and tissues.

Authors:  Reagan McRae; Pritha Bagchi; S Sumalekshmy; Christoph J Fahrni
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

4.  Enhancing the Photostability of Arylvinylenebipyridyl Compounds as Fluorescent Indicators for Intracellular Zinc(II) Ions.

Authors:  Zhao Yuan; Ali H Younes; John R Allen; Michael W Davidson; Lei Zhu
Journal:  J Org Chem       Date:  2015-05-20       Impact factor: 4.354

5.  Reaction of metal-binding ligands with the zinc proteome: zinc sensors and N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine.

Authors:  Jeffrey W Meeusen; Andrew Nowakowski; David H Petering
Journal:  Inorg Chem       Date:  2012-03-01       Impact factor: 5.165

6.  Structurally Characterized Zn2+ Selective Ratiometric Fluorescence Probe in 100 % Water for HeLa Cell Imaging: Experimental and Computational Studies.

Authors:  Babli Kumari; Sisir Lohar; Milan Ghosh; Sabyasachi Ta; Archya Sengupta; Prajna Paramita Banerjee; Ansuman Chattopadhyay; Debasis Das
Journal:  J Fluoresc       Date:  2016-01       Impact factor: 2.217

7.  Zn(II)-coordination modulated ligand photophysical processes - the development of fluorescent indicators for imaging biological Zn(II) ions.

Authors:  Lei Zhu; Zhao Yuan; J Tyler Simmons; Kesavapillai Sreenath
Journal:  RSC Adv       Date:  2014-01-01       Impact factor: 3.361

8.  Integrated and passive 1,2,3-triazolyl groups in fluorescent indicators for zinc(II) ions: thermodynamic and kinetic evaluations.

Authors:  J Tyler Simmons; John R Allen; Deborah R Morris; Ronald J Clark; Cathy W Levenson; Michael W Davidson; Lei Zhu
Journal:  Inorg Chem       Date:  2013-04-26       Impact factor: 5.165

9.  Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy.

Authors:  Liuchun Yang; Reagan McRae; Maged M Henary; Raxit Patel; Barry Lai; Stefan Vogt; Christoph J Fahrni
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-01       Impact factor: 11.205

10.  Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn2+ sensors.

Authors:  Brian A Wong; Simone Friedle; Stephen J Lippard
Journal:  J Am Chem Soc       Date:  2009-05-27       Impact factor: 15.419
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