Literature DB >> 15482921

Structurally simplified macrolactone analogues of halichondrin B.

Boris M Seletsky1, Yuan Wang, Lynn D Hawkins, Monica H Palme, Gregory J Habgood, Lucian V DiPietro, Murray J Towle, Kathleen A Salvato, Bruce F Wels, Kimberley K Aalfs, Yoshito Kishi, Bruce A Littlefield, Melvin J Yu.   

Abstract

A structurally simplified macrolactone analogue of halichondrin B was identified that retains the potent cell growth inhibitory activity of the natural product in vitro.

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Year:  2004        PMID: 15482921     DOI: 10.1016/j.bmcl.2004.08.068

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  12 in total

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