| Literature DB >> 15482481 |
Chao-Tsung Yang1, Roberta D Sengelmann, Stephen L Johnson.
Abstract
A method to specifically ablate melanocytes in a genetically tractable organism would facilitate the analysis of melanocyte regeneration and regulation. We have demonstrated that a Q-switched neodymium:yttrium-aluminum-garnet dermatology laser kills larval melanocytes in zebrafish. Following melanocyte ablation, new melanocytes regenerate from unpigmented precursors. We show that melanocyte regeneration following laser ablation requires kit receptor tyrosine kinase.Entities:
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Year: 2004 PMID： 15482481 DOI： 10.1111/j.0022-202X.2004.23475.x
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551