Literature DB >> 15482417

First episode psychosis: a novel methodology reveals higher than expected incidence; a reality-based population profile in Northumberland, UK.

S E Proctor1, E Mitford, R Paxton.   

Abstract

RATIONALE, AIMS AND
OBJECTIVES: To document the natural history/clinical course of an unselected population presenting with first episode psychosis across a Mental Health Trust.
METHOD: An observational database was set up covering all patients over 15 years of age. Data were collected at presentation and annual follow-up intervals.
RESULTS: A total of 227 patients presented during the 3 years initial study period with a first episode psychosis. The commonest diagnoses were psychotic depression 19%, paranoid schizophrenia 11%, persistent delusional disorder 7% and bipolar affective disorder 7.5% giving an annual incidence of 30.36 per 100 000 population. At presentation, half had been admitted to hospital, nearly half of whom were detained under the Mental Health Act, and only a quarter were currently employed. Twenty-six per cent had an episode of deliberate self-harm and 14% had harmed others. A recurring pattern emerged of over half the patients being no longer in contact with mental health services 1 year after presentation. Data collection is ongoing.
CONCLUSIONS: Clinical and managerial cooperation achieved a practical framework for data collection. This approach in an unselected population of patients yielded new insights into the course of first episode psychosis. The higher incidence than expected from the literature has implications for local strategic planning and provides a framework for detailed evaluation of a complex patient group.

Entities:  

Mesh:

Year:  2004        PMID: 15482417     DOI: 10.1111/j.1365-2753.2003.00474.x

Source DB:  PubMed          Journal:  J Eval Clin Pract        ISSN: 1356-1294            Impact factor:   2.431


  7 in total

1.  Comparing three-year extension of early intervention service to regular care following two years of early intervention service in first-episode psychosis: a randomized single blind clinical trial.

Authors:  Ashok Malla; Ridha Joober; Srividya Iyer; Ross Norman; Norbert Schmitz; Thomas Brown; Danyael Lutgens; Eric Jarvis; Howard C Margolese; Nicola Casacalenda; Amal Abdel-Baki; Eric Latimer; Sally Mustafa; Sherezad Abadi
Journal:  World Psychiatry       Date:  2017-10       Impact factor: 49.548

2.  First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group.

Authors:  Kathleen Crebbin; Emma Mitford; Roger Paxton; Douglas Turkington
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2009-01-27       Impact factor: 4.328

3.  Annual incidence rate of schizophrenia and schizophrenia spectrum disorders in a longitudinal population-based cohort study.

Authors:  Arjen L Sutterland; Jeanne Dieleman; Jitschak G Storosum; Bettie A C Voordouw; Jojanneke Kroon; Joris Veldhuis; Damiaan A J P Denys; Lieuwe de Haan; Miriam C J M Sturkenboom
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2013-01-23       Impact factor: 4.328

Review 4.  Incidence of schizophrenia and other psychoses in England, 1950-2009: a systematic review and meta-analyses.

Authors:  James B Kirkbride; Antonia Errazuriz; Tim J Croudace; Craig Morgan; Daniel Jackson; Jane Boydell; Robin M Murray; Peter B Jones
Journal:  PLoS One       Date:  2012-03-22       Impact factor: 3.240

5.  A systematic review of the evidence of the burden of bipolar disorder in Europe.

Authors:  Liberty Fajutrao; Julie Locklear; Jennifer Priaulx; Anne Heyes
Journal:  Clin Pract Epidemiol Ment Health       Date:  2009-01-23

6.  Drug and alcohol misuse in first episode psychosis: An observational study.

Authors:  Kathleen Crebbin; Emma Mitford; Roger Paxton; Douglas Turkington
Journal:  Neuropsychiatr Dis Treat       Date:  2008-04       Impact factor: 2.570

7.  Biological and psychosocial risk factors for psychotic major depression.

Authors:  M Heslin; R Desai; J M Lappin; K Donoghue; B Lomas; U Reininghaus; A Onyejiaka; T Croudace; P B Jones; R M Murray; P Fearon; G A Doody; P Dazzan; H L Fisher; A Demjaha; T Craig; C Morgan
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2015-10-31       Impact factor: 4.328

  7 in total

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