F Femiano1, F Gombos, C Scully. 1. Stomatology Clinic, II University of Medicine and Surgery, Naples, Italy. femiano@libero.it
Abstract
OBJECTIVE: We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not. METHODS: In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers. RESULTS: The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers. CONCLUSIONS: The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.
OBJECTIVE: We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not. METHODS: In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers. RESULTS: The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers. CONCLUSIONS: The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.