| Literature DB >> 1548170 |
P H Rowland1, S A Center, S A Dougherty.
Abstract
Administration of trimethoprim-sulfadiazine in a dog was associated with vomiting, inappetence, and icterus, and high values of alanine transaminase, aspartate transaminase, alkaline phosphatase, gamma-glutamyltransferase, and total bilirubin concentration. The clinical signs and biochemical abnormalities resolved after discontinuation of the treatment. Histologic examination of sections from a liver biopsy specimen revealed moderate, predominantly portal hepatitis with cholestasis.Entities:
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Year: 1992 PMID： 1548170
Source DB: PubMed Journal: J Am Vet Med Assoc ISSN： 0003-1488 Impact factor: 1.936