| Literature DB >> 15480908 |
Hiroyuki Takei1, Yuichi Komaba, Hiroshi Kitamura, Noriaki Hayama, Hirokazu Osawa, Tetsuya Furukawa, Osamu Hasegawa, Yasuhiko Iino, Yasuo Katayama.
Abstract
A 34-year-old Japanese man admitted to hospital with pneumonia had previously undergone surgery for paranasal sinusitis and also for the clipping of an aneurysm at the origin of the anterior choroidal artery after subarachnoid hemorrhage. Laboratory tests performed at the present admission showed renal insufficiency and serological findings of raised proteinase 3 antineutrophil cytoplasmic antibody level. A renal biopsy was performed that showed diffuse necrotizing glomerulonephritis with fibrocellular crescents. The diagnosis of Wegener's granulomatosis(WG) was confirmed on the basis of the clinical picture, laboratory findings, and biopsies of renal tissues. The disease responded to prednisolone and cyclophosphamide. The association of WG with a ruptured intracranial aneurysm is rare and has not previously been confirmed.Entities:
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Year: 2004 PMID： 15480908 DOI： 10.1007/s10157-004-0280-4
Source DB: PubMed Journal: Clin Exp Nephrol ISSN： 1342-1751 Impact factor: 2.801