Katrin Reuter1, Simone Raugust, Jürgen Bengel, Martin Härter. 1. Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstrasse 5, 79104, Freiburg, Germany. Katrin_Reuter@psyallg.ukl.uni-freiburg.de
Abstract
GOALS OF WORK: In order to obtain references for adequate diagnostic procedures of depressive syndromes in cancer patients, the present study analyzes first the prevalence of somatic, emotional, and cognitive symptoms of depression. In a second part, the ability of diagnostic procedures to discriminate between patients with and without comorbid affective disorder is investigated. PATIENTS AND METHODS: From a cross-sectional survey investigating comorbid mental disorders in cancer patients with standardized clinical assessment, a subsample of 71 patients with current affective disorders and depressive symptoms according to the Diagnostic and Statistic Manual of Mental Disorders, 4th edition (DSM-IV) were analyzed. In addition to patients' symptom patterns, a discriminant analysis including all depressive symptoms was conducted. MAIN RESULTS: Cognitive symptoms are less prevalent in cancer patients than somatic and emotional symptoms. Loss of interest discriminated best between patients with and without diagnosis of comorbid affective disorder. Additionally, decreased energy and fatigue proved to have discriminatory value. CONCLUSIONS: Cognitive symptoms should receive special attention in diagnostic procedures for affective disorders in cancer patients. In spite of possible symptom overlap with the cancer disease and its treatment, fatigue proves to be a useful criteria for diagnosis of depression.
GOALS OF WORK: In order to obtain references for adequate diagnostic procedures of depressive syndromes in cancerpatients, the present study analyzes first the prevalence of somatic, emotional, and cognitive symptoms of depression. In a second part, the ability of diagnostic procedures to discriminate between patients with and without comorbid affective disorder is investigated. PATIENTS AND METHODS: From a cross-sectional survey investigating comorbid mental disorders in cancerpatients with standardized clinical assessment, a subsample of 71 patients with current affective disorders and depressive symptoms according to the Diagnostic and Statistic Manual of Mental Disorders, 4th edition (DSM-IV) were analyzed. In addition to patients' symptom patterns, a discriminant analysis including all depressive symptoms was conducted. MAIN RESULTS: Cognitive symptoms are less prevalent in cancerpatients than somatic and emotional symptoms. Loss of interest discriminated best between patients with and without diagnosis of comorbid affective disorder. Additionally, decreased energy and fatigue proved to have discriminatory value. CONCLUSIONS: Cognitive symptoms should receive special attention in diagnostic procedures for affective disorders in cancerpatients. In spite of possible symptom overlap with the cancer disease and its treatment, fatigue proves to be a useful criteria for diagnosis of depression.
Authors: M H Antoni; J M Lehman; K M Kilbourn; A E Boyers; J L Culver; S M Alferi; S E Yount; B A McGregor; P L Arena; S D Harris; A A Price; C S Carver Journal: Health Psychol Date: 2001-01 Impact factor: 4.267
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Authors: Nina S Kadan-Lottick; Lauren C Vanderwerker; Susan D Block; Baohui Zhang; Holly G Prigerson Journal: Cancer Date: 2005-12-15 Impact factor: 6.860