Literature DB >> 15479876

Targeting the Jak/STAT pathway for immunosuppression.

J J O'shea1.   

Abstract

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Year:  2004        PMID: 15479876      PMCID: PMC1766780          DOI: 10.1136/ard.2004.028290

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


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  67 in total

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2.  Eleven novel JAK3 mutations in patients with severe combined immunodeficiency-including the first patients with mutations in the kinase domain.

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Review 3.  Mutations in severe combined immune deficiency (SCID) due to JAK3 deficiency.

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Review 4.  The use of antibodies against the IL-2 receptor in transplantation.

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5.  Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex.

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6.  Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology.

Authors:  Ulla-Angela Temann; Prabir Ray; Richard A Flavell
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Review 7.  Interleukin-7: master regulator of peripheral T-cell homeostasis?

Authors:  T J Fry; C L Mackall
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8.  Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.

Authors:  A Puel; S F Ziegler; R H Buckley; W J Leonard
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Review 9.  The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c.

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Journal:  Immunol Rev       Date:  1994-04       Impact factor: 12.988

Review 10.  Advances in the understanding and treatment of human severe combined immunodeficiency.

Authors:  R H Buckley
Journal:  Immunol Res       Date:  2000       Impact factor: 4.505

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  37 in total

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Journal:  World J Orthop       Date:  2014-09-18

2.  Expression of Jak3, STAT1, STAT4, and STAT6 in inflammatory arthritis: unique Jak3 and STAT4 expression in dendritic cells in seropositive rheumatoid arthritis.

Authors:  J G Walker; M J Ahern; M Coleman; H Weedon; V Papangelis; D Beroukas; P J Roberts-Thomson; M D Smith
Journal:  Ann Rheum Dis       Date:  2005-08-11       Impact factor: 19.103

Review 3.  Janus kinase 3: the controller and the controlled.

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Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2011-11-29       Impact factor: 3.848

4.  A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation.

Authors:  Wei Wu; Xiao-Hong Sun
Journal:  J Biol Chem       Date:  2011-10-03       Impact factor: 5.157

5.  The role of JAK-3 in regulating TLR-mediated inflammatory cytokine production in innate immune cells.

Authors:  Huizhi Wang; Jonathan Brown; Shegan Gao; Shuang Liang; Ravi Jotwani; Huaxin Zhou; Jill Suttles; David A Scott; Richard J Lamont
Journal:  J Immunol       Date:  2013-06-24       Impact factor: 5.422

6.  Changes in synovial tissue Jak-STAT expression in rheumatoid arthritis in response to successful DMARD treatment.

Authors:  J G Walker; M J Ahern; M Coleman; H Weedon; V Papangelis; D Beroukas; P J Roberts-Thomson; M D Smith
Journal:  Ann Rheum Dis       Date:  2006-06-07       Impact factor: 19.103

Review 7.  Cardiovascular effects of approved drugs for rheumatoid arthritis.

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Review 8.  Current and potential immune therapies and vaccines in the management of psoriasis.

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Review 9.  JAK inhibition using tofacitinib for inflammatory bowel disease treatment: a hub for multiple inflammatory cytokines.

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10.  Generation of a novel CD30+ B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis.

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