Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

Literature DB >> 15479670

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

M C Grimm¹, P Pavli.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2004 PMID： 15479670 PMCID： PMC1774293 DOI： 10.1136/gut.2004.043307

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

× No keyword cloud information.

22 in total

1. Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

Authors: D A O'Neil; E M Porter; D Elewaut; G M Anderson; L Eckmann; T Ganz; M F Kagnoff
Journal: J Immunol Date: 1999-12-15 Impact factor: 5.422

2. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

Authors: T Ayabe; D P Satchell; C L Wilson; W C Parks; M E Selsted; A J Ouellette
Journal: Nat Immunol Date: 2000-08 Impact factor: 25.606

Review 3. Evolutionary diversification of the mammalian defensins.

Authors: A L Hughes
Journal: Cell Mol Life Sci Date: 1999-10-01 Impact factor: 9.261

4. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.

Authors: Y Ogura; N Inohara; A Benito; F F Chen; S Yamaoka; G Nunez
Journal: J Biol Chem Date: 2000-11-21 Impact factor: 5.157

5. Mechanisms for induction of acquired host immunity by neutrophil peptide defensins.

Authors: J W Lillard; P N Boyaka; O Chertov; J J Oppenheim; J R McGhee
Journal: Proc Natl Acad Sci U S A Date: 1999-01-19 Impact factor: 11.205

6. The molecular classification of the clinical manifestations of Crohn's disease.

Authors: Tariq Ahmad; Alessandro Armuzzi; Mike Bunce; Kim Mulcahy-Hawes; Sara E Marshall; Timothy R Orchard; Jonathan Crawshaw; Oliver Large; Arjuna de Silva; Julia T Cook; Martin Barnardo; Sue Cullen; Ken I Welsh; Derek P Jewell
Journal: Gastroenterology Date: 2002-04 Impact factor: 22.682

7. Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.

Authors: K Tani; W J Murphy; O Chertov; R Salcedo; C Y Koh; I Utsunomiya; S Funakoshi; O Asai; S H Herrmann; J M Wang; L W Kwak; J J Oppenheim
Journal: Int Immunol Date: 2000-05 Impact factor: 4.823

8. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells.

Authors: D Yang; Q Chen; O Chertov; J J Oppenheim
Journal: J Leukoc Biol Date: 2000-07 Impact factor: 4.962

9. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.

Authors: Y Ogura; D K Bonen; N Inohara; D L Nicolae; F F Chen; R Ramos; H Britton; T Moran; R Karaliuskas; R H Duerr; J P Achkar; S R Brant; T M Bayless; B S Kirschner; S B Hanauer; G Nuñez; J H Cho
Journal: Nature Date: 2001-05-31 Impact factor: 49.962

10. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.

Authors: Suzanne Lesage; Habib Zouali; Jean-Pierre Cézard; Jean-Frédéric Colombel; Jacques Belaiche; Sven Almer; Curt Tysk; Colm O'Morain; Miquel Gassull; Vibeke Binder; Yigael Finkel; Robert Modigliani; Corinne Gower-Rousseau; Jeanne Macry; Françoise Merlin; Mathias Chamaillard; Anne-Sophie Jannot; Gilles Thomas; Jean-Pierre Hugot
Journal: Am J Hum Genet Date: 2002-03-01 Impact factor: 11.025

5 in total

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

1. Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

2. Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

Review 3. Evolutionary diversification of the mammalian defensins.

4. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB.

5. Mechanisms for induction of acquired host immunity by neutrophil peptide defensins.

6. The molecular classification of the clinical manifestations of Crohn's disease.

7. Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.

8. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells.

9. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease.

10. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease.

Review 1. Paneth cell alpha-defensins: peptide mediators of innate immunity in the small intestine.

Review 2. The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.

3. Colony stimulating factor-1 dependence of paneth cell development in the mouse small intestine.

4. Microbial sensing by the intestinal epithelium in the pathogenesis of inflammatory bowel disease.

5. Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases.