Literature DB >> 1547949

The K2-type killer toxin- and immunity-encoding region from Saccharomyces cerevisiae: structure and expression in yeast.

A Meskauskas1, D Citavicius.   

Abstract

The cDNA copies of M2-1, the larger heat-cleavage product of M2 double-stranded (ds) RNA, have been synthesized, cloned, sequenced and expressed in yeast. This sequence, in combination with the known terminal sequence of M2-1 dsRNA, identifies a translation reading frame for a 362-amino-acid protein of 38.7 kDa, similar in size to the one of several protein species produced from M2-1 dsRNA in vitro translation. The expression of this cDNA clone in yeast confers both killer and immunity phenotypes.

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Year:  1992        PMID: 1547949     DOI: 10.1016/0378-1119(92)90615-v

Source DB:  PubMed          Journal:  Gene        ISSN: 0378-1119            Impact factor:   3.688


  8 in total

Review 1.  Yeast killer systems.

Authors:  W Magliani; S Conti; M Gerloni; D Bertolotti; L Polonelli
Journal:  Clin Microbiol Rev       Date:  1997-07       Impact factor: 26.132

2.  A Novel Saccharomyces cerevisiae Killer Strain Secreting the X Factor Related to Killer Activity and Inhibition of S. cerevisiae K1, K2 and K28 Killer Toxins.

Authors:  Vytautas Melvydas; Ieva Bružauskaitė; Genovaitė Gedminienė; Rimantas Šiekštelė
Journal:  Indian J Microbiol       Date:  2016-04-29       Impact factor: 2.461

3.  Yeast Viral Killer Toxin K1 Induces Specific Host Cell Adaptions via Intrinsic Selection Pressure.

Authors:  Stefanie Gier; Martin Simon; Gilles Gasparoni; Salem Khalifa; Marcel H Schulz; Manfred J Schmitt; Frank Breinig
Journal:  Appl Environ Microbiol       Date:  2020-02-03       Impact factor: 4.792

4.  Yeast β-1,6-glucan is a primary target for the Saccharomyces cerevisiae K2 toxin.

Authors:  Juliana Lukša; Monika Podoliankaitė; Iglė Vepštaitė; Živilė Strazdaitė-Žielienė; Jaunius Urbonavičius; Elena Servienė
Journal:  Eukaryot Cell       Date:  2015-02-20

5.  High-yield expression in Escherichia coli, purification and application of budding yeast K2 killer protein.

Authors:  Monika Podoliankaitė; Juliana Lukša; Gintautas Vyšniauskis; Jolanta Sereikaitė; Vytautas Melvydas; Saulius Serva; Elena Servienė
Journal:  Mol Biotechnol       Date:  2014-07       Impact factor: 2.695

6.  Immunity to killer toxin K1 is connected with the Golgi-to-vacuole protein degradation pathway.

Authors:  K Valis; T Masek; D Novotná; M Pospísek; B Janderová
Journal:  Folia Microbiol (Praha)       Date:  2006       Impact factor: 2.629

7.  Screening the budding yeast genome reveals unique factors affecting K2 toxin susceptibility.

Authors:  Elena Servienė; Juliana Lukša; Irma Orentaitė; Denis L J Lafontaine; Jaunius Urbonavičius
Journal:  PLoS One       Date:  2012-12-05       Impact factor: 3.240

Review 8.  New developments in fungal virology.

Authors:  S A Ghabrial
Journal:  Adv Virus Res       Date:  1994       Impact factor: 9.937

  8 in total

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