Literature DB >> 15476623

Bivalirudin versus heparin as an antithrombotic agent in patients treated with a sirolimus-eluting stent.

Seung-Woon Rha1, Pramod K Kuchulakanti, Rajbabu Pakala, Edouard Cheneau, Jana A Fournadjiev, Ellen Pinnow, Afework Gebreeyesus, George Aggrey, Zuyue Wang, Augusto D Pichard, Lowell F Satler, Kenneth M Kent, Joseph Lindsay, Ron Waksman.   

Abstract

Bivalirudin (Angiomax) is increasingly used as a substitute for heparin in a variety of percutaneous coronary interventions. This retrospective, observational study aimed to evaluate the efficacy and safety of bivalirudin compared with heparin as an antithrombotic regimen in patients treated with sirolimus-eluting stents (Cypher) and found that bivalirudin is clinically safe and feasible, with fewer vascular and ischemic complications compared with heparin.

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Year:  2004        PMID: 15476623     DOI: 10.1016/j.amjcard.2004.06.065

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  3 in total

Review 1.  Bivalirudin: a review of its use in patients undergoing percutaneous coronary intervention.

Authors:  Marit D Moen; Gillian M Keating; Keri Wellington
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  Darwin and the survival of the fittest in modern interventional cardiology.

Authors:  V K Bhatia; C Di Mario
Journal:  Heart       Date:  2006-01-31       Impact factor: 5.994

3.  Quantitation of bivalirudin, a novel anticoagulant peptide, in human plasma by LC-MS/MS: Method development, validation and application to pharmacokinetics.

Authors:  Xiao-Jiao Li; Yan-Tong Sun; Lei Yin; Xue-Ju Zhang; Yan Yang; J Paul Fawcett; Yi-Min Cui; Jing-Kai Gu
Journal:  J Pharm Anal       Date:  2012-11-07
  3 in total

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