Literature DB >> 15475626

Cytoplasmic tail adaptors of Alzheimer's amyloid-beta protein precursor.

Masaoki Kawasumi1, Shuji Matsuda, Masaaki Matsuoka, Ikuo Nishimoto.   

Abstract

Alzheimer's disease is characterized pathologically by senile plaques in the brain. The major component of senile plaques is amyloid-beta (Abeta), which is cleaved from Alzheimer's Abeta protein precursor (AbetaPP). Recently, information regarding the cytoplasmic tail of AbetaPP has started to emerge, opening up various insights into the physiological roles of AbetaPP and its pathological role in Alzheimer's disease. The cytoplasmic domain of AbetaPP shares the evolutionarily conserved GYENPTY motif, which binds to a number of adaptor proteins containing the phosphotyrosine interaction domain (PID). Among the PID-containing proteins, this article focuses on four groups of adaptor proteins of AbetaPP: Fe65, X11, mDab1, and c-Jun N-terminal kinase-interacting protein 1b/islet-brain 1.

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Year:  2004        PMID： 15475626     DOI： 10.1385/MN:30:2:185

Source DB:  PubMed          Journal:  Mol Neurobiol        ISSN： 0893-7648            Impact factor:   5.590


  121 in total

1.  Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP.

Authors:  A Kamal; A Almenar-Queralt; J F LeBlanc; E A Roberts; L S Goldstein
Journal:  Nature       Date:  2001-12-06       Impact factor: 49.962

2.  Reelin binds alpha3beta1 integrin and inhibits neuronal migration.

Authors:  L Dulabon; E C Olson; M G Taglienti; S Eisenhuth; B McGrath; C A Walsh; J A Kreidberg; E S Anton
Journal:  Neuron       Date:  2000-07       Impact factor: 17.173

3.  Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.

Authors:  Z Zhang; C H Lee; V Mandiyan; J P Borg; B Margolis; J Schlessinger; J Kuriyan
Journal:  EMBO J       Date:  1997-10-15       Impact factor: 11.598

4.  The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates.

Authors:  S K Kim; H R Horvitz
Journal:  Genes Dev       Date:  1990-03       Impact factor: 11.361

5.  A cytoplasmic inhibitor of the JNK signal transduction pathway.

Authors:  M Dickens; J S Rogers; J Cavanagh; A Raitano; Z Xia; J R Halpern; M E Greenberg; C L Sawyers; R J Davis
Journal:  Science       Date:  1997-08-01       Impact factor: 47.728

6.  Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein.

Authors:  H Sudo; H Jiang; T Yasukawa; Y Hashimoto; T Niikura; M Kawasumi; S Matsuda; Y Takeuchi; S Aiso; M Matsuoka; Y Murayama; I Nishimoto
Journal:  Mol Cell Neurosci       Date:  2000-12       Impact factor: 4.314

7.  FE65 in Alzheimer's disease: neuronal distribution and association with neurofibrillary tangles.

Authors:  B Delatour; L Mercken; K H El Hachimi; M A Colle; L Pradier; C Duyckaerts
Journal:  Am J Pathol       Date:  2001-05       Impact factor: 4.307

8.  Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice.

Authors:  M Sheldon; D S Rice; G D'Arcangelo; H Yoneshima; K Nakajima; K Mikoshiba; B W Howell; J A Cooper; D Goldowitz; T Curran
Journal:  Nature       Date:  1997-10-16       Impact factor: 49.962

9.  JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65.

Authors:  Meir H Scheinfeld; Shuji Matsuda; Luciano D'Adamio
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-31       Impact factor: 11.205

10.  LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction.

Authors:  J S Simske; S M Kaech; S A Harp; S K Kim
Journal:  Cell       Date:  1996-04-19       Impact factor: 41.582
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  4 in total

Review 1.  Role of APP Interactions with Heterotrimeric G Proteins: Physiological Functions and Pathological Consequences.

Authors:  Philip F Copenhaver; Donat Kögel
Journal:  Front Mol Neurosci       Date:  2017-01-31       Impact factor: 5.639

2.  Loss of PAFAH1B2 reduces amyloid-β generation by promoting the degradation of amyloid precursor protein C-terminal fragments.

Authors:  Richard M Page; Anna Münch; Thomas Horn; Peer-Hendrik Kuhn; Alessio Colombo; Orly Reiner; Michael Boutros; Harald Steiner; Stefan F Lichtenthaler; Christian Haass
Journal:  J Neurosci       Date:  2012-12-12       Impact factor: 6.167

Review 3.  Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptors.

Authors:  Bor Luen Tang
Journal:  Cell Adh Migr       Date:  2009-01-21       Impact factor: 3.405

4.  Multisite tyrosine phosphorylation of the N-terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein.

Authors:  Christopher J R Dunning; Hannah L Black; Katie L Andrews; Elizabeth C Davenport; Michael Conboy; Sangeeta Chawla; Adam A Dowle; David Ashford; Jerry R Thomas; Gareth J O Evans
Journal:  J Neurochem       Date:  2016-03-01       Impact factor: 5.372
  4 in total

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