POPULATIONS AND METHODS: In order to analyze epidemiological and clinical characteristics of enuresis in children with sickle cell disease, and identify risk and aetiological factors, 987 subjects (aged 5-20 years) took part in a cross-sectional study. These children were divided into two groups: group 1 consisted of 456 homozygous children with sickle cell disease (haemoglobin SS), while group 2 consisted of 531 normal children. These groups were paired according to age and sex. RESULTS: The prevalence of enuresis was 50.9% in group 1 and 16.4% in group 2, and was significantly higher (P < 0.05) in the girls. The frequency decreased significantly between the ages of 5-20. At age 16, frequency of enuretic children with sickle cell disease remained statistically greater (15.9% vs. 8.0%). The frequency of wet nights was higher (P < 0.05) in group 1. In addition, anaemia crisis and painful crisis were related to prevalence of enuresis. There was a significant (P < 0.01) negative correlation between haemoglobin F percentage and prevalence of enuresis. CONCLUSION: Enuresis is frequent in children with sickle cell disease and its intensity is linked to severity of disease.
POPULATIONS AND METHODS: In order to analyze epidemiological and clinical characteristics of enuresis in children with sickle cell disease, and identify risk and aetiological factors, 987 subjects (aged 5-20 years) took part in a cross-sectional study. These children were divided into two groups: group 1 consisted of 456 homozygous children with sickle cell disease (haemoglobin SS), while group 2 consisted of 531 normal children. These groups were paired according to age and sex. RESULTS: The prevalence of enuresis was 50.9% in group 1 and 16.4% in group 2, and was significantly higher (P < 0.05) in the girls. The frequency decreased significantly between the ages of 5-20. At age 16, frequency of enuretic children with sickle cell disease remained statistically greater (15.9% vs. 8.0%). The frequency of wet nights was higher (P < 0.05) in group 1. In addition, anaemia crisis and painful crisis were related to prevalence of enuresis. There was a significant (P < 0.01) negative correlation between haemoglobin F percentage and prevalence of enuresis. CONCLUSION:Enuresis is frequent in children with sickle cell disease and its intensity is linked to severity of disease.
Authors: Uzoma A Anele; Belinda F Morrison; Marvin E Reid; Wendy Madden; Shara Foster; Arthur L Burnett Journal: Neurourol Urodyn Date: 2015-04-14 Impact factor: 2.696
Authors: Rima S Zahr; Juan Ding; Guolian Kang; Winfred C Wang; Jane S Hankins; Kenneth I Ataga; Jeffrey D Lebensburger; Jerlym S Porter Journal: J Pediatr Hematol Oncol Date: 2022-02-18 Impact factor: 1.170
Authors: Alana de Medeiros Nelli; Flavia Cristina de Carvalho Mrad; Mateus de Andrade Alvaia; Heros Aureliano Antunes da Silva Maia; Carina Oliveira Silva Guimarães; Evanilda Souza de Santana Carvalho; Cristiano Mendes Gomes; José Murillo Bastos; Jose de Bessa Journal: Int Braz J Urol Date: 2019 Sep-Oct Impact factor: 3.050