| Literature DB >> 15475070 |
Hiroshi Kojima1, Yuichi Hasegawa, Kazumi Suzukawa, Harumi Y Mukai, Shin Kaneko, Toshitaka Kobayashi, Masaharu Kamoshita, Atsushi Shinagawa, Takuya Komeno, Tsunehiko Komatsu, Shoichi Mitsuhashi, Yasuhiro Kawachi, Yoriko Yamashita, Naoyoshi Mori, Toshiro Nagasawa.
Abstract
Clinicopathological features of 36 patients, male: 58.3%; median: 68 years, with "peripheral T-cell lymphoma, unspecified" diagnosed by the WHO criteria were reviewed. Majority (69.4%) had stage IV disease with frequent involvements into bone marrow, spleen, liver, and skin. According to the IPI, 72.2% were categorized as high or high-intermediate risk group. CR and PR were achieved in 12 and 10 out of 31 patients treated by CHOP-based chemotherapy, respectively. One- and two-year overall survivals were 60.6 and 25.0%, respectively. Performance status, serum LDH, and B symptom were significant prognostic factors. Survival of CD4-/CD8+ cases, corresponding to cytotoxic T-cell lymphoma, was significantly worse than that of CD4+/CD8-.Entities:
Mesh:
Year: 2004 PMID: 15475070 DOI: 10.1016/j.leukres.2004.04.016
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156