Literature DB >> 15474864

Anti-interleukin-5 therapy for asthma and hypereosinophilic syndrome.

A Barry Kay1, Amy D Klion.   

Abstract

Interleukin 5 (IL-5) is a key cytokine in the regulation of eosinophilia and eosinophil activation in humans. Monoclonal antibodies to anti-IL-5 have become available for use in clinical studies in humans. This article discusses the rationale for the use of anti-IL-5 therapy in asthma and hypereosinophilic syndrome and summarizes the available clinical data on the use of anti-IL-5 to treat these disorders.

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Year:  2004        PMID： 15474864     DOI： 10.1016/j.iac.2004.06.007

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN： 0889-8561            Impact factor:   3.479


  13 in total

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