Literature DB >> 15474860

Role of tumor necrosis factor alpha in asthma.

K Suresh Babu1, Donna E Davies, Stephen T Holgate.   

Abstract

Asthma is a heterogeneous disease in which various cytokines orchestrate airway inflammation. Tumor necrosis alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the modulation of inflammation in various diseases, including asthma. Although TNF-alpha blocking strategies have been an effective therapeutic modality in diseases such as rheumatoid arthritis, their role in asthma and the effects of the blockade in asthma is poorly understood. This article examines the role of TNF-alpha in asthma and the effects of blocking TNF-alpha as a possible therapeutic option in patients with severe corticosteroid-dependent asthma.

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Year:  2004        PMID: 15474860     DOI: 10.1016/j.iac.2004.06.010

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN: 0889-8561            Impact factor:   3.479


  11 in total

1.  Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma.

Authors:  Melissa E Munroe; Thomas R Businga; Joel N Kline; Gail A Bishop
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2.  Associations of tumor necrosis factor G-308A with childhood asthma and wheezing.

Authors:  Yu-Fen Li; W James Gauderman; Ed Avol; Louis Dubeau; Frank D Gilliland
Journal:  Am J Respir Crit Care Med       Date:  2006-02-02       Impact factor: 21.405

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Authors:  Jiyoun Kim; Daniel G Remick
Journal:  Curr Allergy Asthma Rep       Date:  2007-05       Impact factor: 4.806

Review 4.  Physiology and pathophysiology of canonical transient receptor potential channels.

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Journal:  FASEB J       Date:  2008-10-21       Impact factor: 5.191

5.  The possible role of trauma in skin tags through the release of mast cell mediators.

Authors:  Omar S El Safoury; Marwa M Fawzy; Rania M Abdel Hay; Akmal S Hassan; Zeinab M El Maadawi; Laila A Rashed
Journal:  Indian J Dermatol       Date:  2011-11       Impact factor: 1.494

6.  Immunomodulatory and Anti-Inflammatory Potential of Curcumin for the Treatment of Allergic Asthma: Effects on Expression Levels of Pro-inflammatory Cytokines and Aquaporins.

Authors:  Hira Shahid; Muhammad Shahzad; Arham Shabbir; Gulpash Saghir
Journal:  Inflammation       Date:  2019-12       Impact factor: 4.657

Review 7.  Asthma in children and adolescents: a comprehensive approach to diagnosis and management.

Authors:  Christopher Chang
Journal:  Clin Rev Allergy Immunol       Date:  2012-08       Impact factor: 8.667

8.  Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17.

Authors:  Jeffrey N Harding; Maureen Gross; Vivek Patel; Steven Potter; Stephania A Cormier
Journal:  Respir Res       Date:  2021-10-26

9.  Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma.

Authors:  Hao Wu; Isabelle Romieu; Juan-Jose Sienra-Monge; Blanca Estela del Rio-Navarro; Daniel M Anderson; Erin W Dunn; Lori L Steiner; Irma del Carmen Lara-Sanchez; Stephanie J London
Journal:  Environ Health Perspect       Date:  2007-01-16       Impact factor: 9.031

10.  MicroRNA-146a is induced by inflammatory stimuli in airway epithelial cells and augments the anti-inflammatory effects of glucocorticoids.

Authors:  Kristin A Lambert; Alanna N Roff; Ronaldo P Panganiban; Scott Douglas; Faoud T Ishmael
Journal:  PLoS One       Date:  2018-10-09       Impact factor: 3.240

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