Solitary pulmonary nodule in secondary syphilis.

A case of secondary syphilis with a solitary right upper-lobe nodule is presented. Patient presented without any pulmonary complaints or findings. This mass disappeared with residual scar after a full course of penicillin therapy. Our report is the first in the literature that reports a solitary nodule in the upper lobes in secondary syphilis. Previous reports showed nodules only in lower lobes. Our patient also presented with a rectal mass that disappeared on anti-syphilitic therapy.