| Literature DB >> 15474104 |
Abstract
Hearing loss can be caused by acoustic trauma, aging, ototoxic medications, and various other causes. At the cellular level hearing loss seems to be mediated by reactive oxygen species and ultimately through the activation of apoptotic mechanisms. This article explains the cellular and molecular mechanisms of hearing loss and presents medications that could be used in the intratympanic treatment of hearing loss.Entities:
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Year: 2004 PMID： 15474104 DOI： 10.1016/j.otc.2004.03.004
Source DB: PubMed Journal: Otolaryngol Clin North Am ISSN： 0030-6665 Impact factor: 3.346