Literature DB >> 15473660

Pulsatilla saponin D: the antitumor principle from Pulsatilla koreana.

Yong Kim1, Seong-Cheol Bang, Ji-Hyun Lee, Byung-Zun Ahn.   

Abstract

By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82%) at the dose of 6.4 mg/kg on the BDF1 mice bearing LLC cells.

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Year:  2004        PMID： 15473660     DOI： 10.1007/BF02975843

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  12 in total

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Authors:  E Mazzio; R Badisa; N Mack; S Deiab; K F A Soliman
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Authors:  Zhuo Xiang; Qing Miao; Jin Zhang; Yang Liu; Guoxin Liu; Shuyi Xue; Xu Liu; Zhe Zhang; Lixia Shen; Bangguo Liu; Yu Zhou; Ting Miao
Journal:  Oncol Rep       Date:  2021-04-28       Impact factor: 3.906

4.  Extracts from Pulsatilla patens target cancer-related signaling pathways in HeLa cells.

Authors:  Grażyna Łaska; Magdalena Maciejewska-Turska; Elwira Sieniawska; Łukasz Świątek; David S Pasco; Premalatha Balachandran
Journal:  Sci Rep       Date:  2021-05-20       Impact factor: 4.379

5.  Complete sequence analysis and antiviral screening of medicinal plants for human coxsackievirus a16 isolated in Korea.

Authors:  Jae-Hyoung Song; Kwisung Park; Aeri Shim; Bo-Eun Kwon; Jae-Hee Ahn; Young Jin Choi; Jae Kyung Kim; Sang-Gu Yeo; Kyungah Yoon; Hyun-Jeong Ko
Journal:  Osong Public Health Res Perspect       Date:  2015-01-09

6.  Anti-Inflammatory and PPAR Transactivational Effects of Oleanane-Type Triterpenoid Saponins from the Roots of Pulsatilla koreana.

Authors:  Wei Li; Xi Tao Yan; Ya Nan Sun; Thi Thanh Ngan; Sang Hee Shim; Young Ho Kim
Journal:  Biomol Ther (Seoul)       Date:  2014-07       Impact factor: 4.634

7.  Alpha-Hederin, the Active Saponin of Nigella sativa, as an Anticancer Agent Inducing Apoptosis in the SKOV-3 Cell Line.

Authors:  Anna Adamska; Justyna Stefanowicz-Hajduk; J Renata Ochocka
Journal:  Molecules       Date:  2019-08-15       Impact factor: 4.411

8.  Synthesis, Biological Evaluation, and Mode of Action of Pulsatilla Saponin D Derivatives as Promising Anticancer Agents.

Authors:  Yuanying Fang; Daoyong Hu; Huilan Li; Jianguo Hu; Yanhua Liu; Zhifeng Li; Guoliang Xu; Lanying Chen; Yi Jin; Shilin Yang; Zunhua Yang
Journal:  Front Pharmacol       Date:  2019-10-15       Impact factor: 5.810

9.  Isolation of nematicidal triterpenoid saponins from Pulsatilla koreana root and their activities against Meloidogyne incognita.

Authors:  Wei Li; Ya Nan Sun; Xi Tao Yan; Seo Young Yang; Suk Jun Lee; Hyo Jeung Byun; Chang Sup Moon; Byung Soo Han; Young Ho Kim
Journal:  Molecules       Date:  2013-05-08       Impact factor: 4.411

10.  SB365, Pulsatilla Saponin D Induces Caspase-Independent Cell Death and Augments the Anticancer Effect of Temozolomide in Glioblastoma Multiforme Cells.

Authors:  Jun-Man Hong; Jin-Hee Kim; Hyemin Kim; Wang Jae Lee; Young-Il Hwang
Journal:  Molecules       Date:  2019-09-05       Impact factor: 4.411
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