| Literature DB >> 15473073 |
Ray Paton1, Richard Gregory, Costas Vlachos, Jon Saunders, Henry Wu.
Abstract
We present two approaches to the individual-based modeling (IbM) of bacterial ecologies and evolution using computational tools. The IbM approach is introduced, and its important complementary role to biosystems modeling is discussed. A fine-grained model of bacterial evolution is then presented that is based on networks of interactivity between computational objects representing genes and proteins. This is followed by a coarser grained agent-based model, which is designed to explore the evolvability of adaptive behavioral strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of the two proposed individual-based bacterial models are discussed, and some results from simulation experiments are presented, illustrating their adaptive properties.Mesh:
Substances:
Year: 2004 PMID: 15473073 DOI: 10.1109/tnb.2004.833701
Source DB: PubMed Journal: IEEE Trans Nanobioscience ISSN: 1536-1241 Impact factor: 2.935