Literature DB >> 15472354

Universal high-level primary metronidazole resistance in Helicobacter pylori isolated from children in Egypt.

May Sherif1, Zaynab Mohran, Hanan Fathy, David M Rockabrand, Patrick J Rozmajzl, Robert W Frenck.   

Abstract

Antimicrobial susceptibility testing was performed on 48 isolates of Helicobacter pylori recovered from Egyptian children undergoing routine endoscopies. The isolates were universally highly resistant to metronidazole, but resistance to other tested antimicrobial agents was rare (4% for clarithromycin, erythromycin, and azithromycin resistance versus 2% for ciprofloxacin and ampicillin resistance). Use of metronidazole for the treatment of H. pylori in Egypt should be avoided.

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Year:  2004        PMID： 15472354      PMCID： PMC522302          DOI： 10.1128/JCM.42.10.4832-4834.2004

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  21 in total

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