Literature DB >> 15471183

[Diagnosis and therapy of restless legs syndrome in the doctor's office].

Michael Saletu1, Martina Esberger-Chowdhury, Josef Zeitlhofer, Lüder Deecke.   

Abstract

BACKGROUND: Restless legs syndrome (RLS) is a movement and sleep disorder with leg dysesthesias with a high prevalence (9-18% in Austria). AIM OF THE STUDY: Determination of frequency, diagnosis and therapy of RLS in general practitioner and specialist offices.
METHODS: Telephone survey of a random sample of 120 general practitioners, 100 neurologists and 80 specialists in internal medicine.
RESULTS: 69% of the whole sample of doctors reported seeing 1 to 10 RLS patients, but in proportion to the prevalence of these two conditions fewer cases of RLS than of Parkinson's disease are treated. In all three groups of doctors, 84% consider the 4 key symptoms (urge to move the legs accompanied or caused by dysesthesia; worsening of symptoms at rest or inactivity; relief by activity; worsening of symptoms in the evening/at night) the most important diagnostic criteria for RLS, followed by a complaint of disturbed sleep (75%), daytime tiredness (43%) and dopaminergic responsiveness in a therapeutic trial (29%). 83% of general practitioners and 86% of medical specialists refer their RLS patients to a neurologist, 19% to a polysomnographic examination. 75% of doctors decide for pharmacological treatment of RLS, 18% for psychotherapy, 15% for household remedies. 54% of all doctors (70% of the neurologists, 68% of the GPs, 48% of the medical specialists) prescribe dopamine agonists. L-Dopa is used by 49% (61% of the neurologists, 42% of the GPs, 44% of the medical specialists). 17% prescribe GABAergic drugs, 6% opiates. 51% would be highly interested in obtaining a drug specifically registered for the treatment of RLS.
CONCLUSION: RLS is not as well known as Parkinson's disease. Thus providing doctors with relevant information and further education programs on this subject seems desirable. In Austrian doctors' offices the diagnosis of RLS is usually obtained clinically on the basis of the 4 key symptoms. Patients suffering from insomnia of multifactorial pathogenesis should be referred to an outpatient clinic for sleep disorders with an associated sleep laboratory. Especially neurologists and GPs consider dopamine agonists the treatment of first choice, closely followed by L-Dopa.

Entities:  

Mesh:

Year:  2004        PMID: 15471183     DOI: 10.1007/BF03217709

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN: 0043-5325            Impact factor:   1.704


  25 in total

1.  Sleep laboratory studies in restless legs syndrome patients as compared with normals and acute effects of ropinirole. 1. Findings on objective and subjective sleep and awakening quality.

Authors:  B Saletu; G Gruber; M Saletu; N Brandstätter; C Hauer; W Prause; K Ritter; G Saletu-Zyhlarz
Journal:  Neuropsychobiology       Date:  2000       Impact factor: 2.328

2.  Epidemiology of restless legs symptoms in adults.

Authors:  B Phillips; T Young; L Finn; K Asher; W A Hening; C Purvis
Journal:  Arch Intern Med       Date:  2000-07-24

3.  Dopaminergic treatment of restless legs and rebound phenomenon.

Authors:  C Guilleminault; M Cetel; P Philip
Journal:  Neurology       Date:  1993-02       Impact factor: 9.910

4.  [Daytime tiredness correlated with nocturnal respiratory and arousal variables in patients with sleep apnea: polysomnographic and EEG mapping studies].

Authors:  M Saletu; C Hauer; P Anderer; G Saletu-Zyhlarz; G Gruber; S Oberndorfer; M Mandl; R Popovic; B Saletu
Journal:  Wien Klin Wochenschr       Date:  2000-03-24       Impact factor: 1.704

5.  EEG mapping, psychometric, and polysomnographic studies in restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) patients as compared with normal controls.

Authors:  B Saletu; P Anderer; M Saletu; C Hauer; L Lindeck-Pozza; G Saletu-Zyhlarz
Journal:  Sleep Med       Date:  2002-11       Impact factor: 3.492

6.  Acute placebo-controlled sleep laboratory studies and clinical follow-up with pramipexole in restless legs syndrome.

Authors:  M Saletu; P Anderer; G Saletu-Zyhlarz; C Hauer; B Saletu
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2002-08       Impact factor: 5.270

7.  Quality of life in nonorganic and organic sleep disorders: I. Comparison with normative data.

Authors:  Bernd Saletu; Wolfgang Prause; Henriette Löffler-Stastka; Peter Anderer; Nadja Brandstätter; Ali Zoghlami; Gerda Saletu-Zyhlarz; Heinz Katschnig
Journal:  Wien Klin Wochenschr       Date:  2003-04-30       Impact factor: 1.704

8.  [Epidemiology of sleep disorders in Austria].

Authors:  J Zeitlhofer; A Rieder; G Kapfhammer; J Bolitschek; A Skrobal; B Holzinger; H Lechner; B Saletu; M Kunze
Journal:  Wien Klin Wochenschr       Date:  1994       Impact factor: 1.704

9.  Acute double-blind, placebo-controlled sleep laboratory and clinical follow-up studies with a combination treatment of rr-L-dopa and sr-L-dopa in restless legs syndrome.

Authors:  M Saletu; P Anderer; B Högl; G Saletu-Zyhlarz; A Kunz; W Poewe; B Saletu
Journal:  J Neural Transm (Vienna)       Date:  2003-06       Impact factor: 3.575

Review 10.  Restless legs syndrome: an update on treatment options.

Authors:  Anthony H V Schapira
Journal:  Drugs       Date:  2004       Impact factor: 9.546

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