Literature DB >> 15470909

Linear energy transfer dependence of a normoxic polymer gel dosimeter investigated using proton beam absorbed dose measurements.

Helen Gustavsson1, Sven A J Bäck, Joakim Medin, Erik Grusell, Lars E Olsson.   

Abstract

Three-dimensional dosimetry with good spatial resolution can be performed using polymer gel dosimetry, which has been investigated for dosimetry of different types of particles. However, there are only sparse data concerning the influence of the linear energy transfer (LET) properties of the radiation on the gel absorbed dose response. The purpose of this study was to investigate possible LET dependence for a polymer gel dosimeter using proton beam absorbed dose measurements. Polymer gel containing the antioxidant tetrakis(hydroxymethyl)phosphonium (THP) was irradiated with 133 MeV monoenergetic protons, and the gel absorbed dose response was evaluated using MRI. The LET distribution for a monoenergetic proton beam was calculated as a function of depth using the Monte Carlo code PETRA. There was a steep increase in the Monte Carlo calculated LET starting at the depth corresponding to the front edge of the Bragg peak. This increase was closely followed by a decrease in the relative detector sensitivity (Srel = Dgel/Ddiode), indicating that the response of the polymer gel detector was dependent on LET. The relative sensitivity was 0.8 at the Bragg peak, and reached its minimum value at the end of the proton range. No significant effects in the detector response were observed for LET < 4.9 keV microm(-1), thus indicating that the behaviour of the polymer gel dosimeter would not be altered for the range of LET values expected in the case of photons or electrons in a clinical range of energies.

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Year:  2004        PMID: 15470909     DOI: 10.1088/0031-9155/49/17/002

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  10 in total

1.  Verification of proton range, position, and intensity in IMPT with a 3D liquid scintillator detector system.

Authors:  L Archambault; F Poenisch; N Sahoo; D Robertson; A Lee; M T Gillin; R Mohan; S Beddar
Journal:  Med Phys       Date:  2012-03       Impact factor: 4.071

2.  Improved MAGIC gel for higher sensitivity and elemental tissue equivalent 3D dosimetry.

Authors:  Xuping Zhu; Timothy G Reese; Elizabeth M Crowley; Georges El Fakhri
Journal:  Med Phys       Date:  2010-01       Impact factor: 4.071

3.  Exploration of the potential of liquid scintillators for real-time 3D dosimetry of intensity modulated proton beams.

Authors:  Sam Beddar; Louis Archambault; Narayan Sahoo; Falk Poenisch; George T Chen; Michael T Gillin; Radhe Mohan
Journal:  Med Phys       Date:  2009-05       Impact factor: 4.071

Review 4.  Polymer gel dosimetry.

Authors:  C Baldock; Y De Deene; S Doran; G Ibbott; A Jirasek; M Lepage; K B McAuley; M Oldham; L J Schreiner
Journal:  Phys Med Biol       Date:  2010-02-11       Impact factor: 3.609

5.  Radiological properties of nanocomposite Fricke gel dosimeters for heavy ion beams.

Authors:  Takuya Maeyama; Nobuhisa Fukunishi; Kenichi L Ishikawa; Kazuaki Fukasaku; Shigekazu Fukuda
Journal:  J Radiat Res       Date:  2016-03-10       Impact factor: 2.724

Review 6.  Three-dimensional radiation dosimetry using polymer gel and solid radiochromic polymer: From basics to clinical applications.

Authors:  Yoichi Watanabe; Leighton Warmington; N Gopishankar
Journal:  World J Radiol       Date:  2017-03-28

7.  Issues involved in the quantitative 3D imaging of proton doses using optical CT and chemical dosimeters.

Authors:  Simon Doran; Tina Gorjiara; Andrzej Kacperek; John Adamovics; Zdenka Kuncic; Clive Baldock
Journal:  Phys Med Biol       Date:  2015-01-02       Impact factor: 3.609

Review 8.  Radiation Dosimetry by Use of Radiosensitive Hydrogels and Polymers: Mechanisms, State-of-the-Art and Perspective from 3D to 4D.

Authors:  Yves De Deene
Journal:  Gels       Date:  2022-09-19

9.  Empirical quenching correction in radiochromic silicone-based three-dimensional dosimetry of spot-scanning proton therapy.

Authors:  Lia Barbosa Valdetaro; Ellen Marie Høye; Peter Sandegaard Skyt; Jørgen Breede Baltzer Petersen; Peter Balling; Ludvig Paul Muren
Journal:  Phys Imaging Radiat Oncol       Date:  2021-04-12

10.  MAGIC polymer gel for dosimetric verification in boron neutron capture therapy.

Authors:  Jouni Uusi-Simola; Sami Heikkinen; Petri Kotiluoto; Tom Serén; Tiina Seppälä; Iiro Auterinen; Sauli Savolainen
Journal:  J Appl Clin Med Phys       Date:  2007-04-30       Impact factor: 2.102

  10 in total

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