Pearl H Seo1, Carl F Pieper, Harvey Jay Cohen. 1. Division of Geriatrics, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. seo00003@mc.duke.edu
Abstract
BACKGROUND: Older cancer survivors use healthcare services to an increased extent relative to their counterparts who have no history of malignant disease. In the current study, the authors set out to assess the effects of cancer history and comorbid conditions on healthcare use and mortality. METHODS: Using information from the 1992 North Carolina Established Populations for Epidemiologic Study of the Elderly database, study participants were classified as having no history of malignant disease or as having a recent (cancer diagnosed < 1 year earlier), intermediate (cancer diagnosed 1-6 years earlier), or remote (cancer diagnosed > 6 years earlier) history of malignancy. Overall, 15 different comorbid conditions were ascertained. Logistic regression models adjusted for sociodemographic factors, tobacco and alcohol use, and functional measures were used to determine the risk of emergency room, hospital, and nursing home (NH) admission in 1992 and also in 1996 according to history of malignancy and presence of comorbid conditions. Using data from the National Death Registry, a similar controlled analysis of 7-year mortality also was performed. RESULTS: There were 2567 participants in the current study (mean age, 79 years; range, 71-102 years); 69% of all participants were women, 55% were African American, and 14% reported having a history of malignancy. Participants with a history of malignancy had an average of 3 comorbid conditions, and differences across groups in terms of cardiovascular and lung disease incidence were noted. Controlled analyses revealed that recent cancer history (odds ratio [OR], 15.5; 95% confidence interval [CI], 7.0-34.2) and intermediate cancer history (OR, 2.1; 95% CI, 1.4-3.3) were associated with same-year hospital admission. In addition, having a recent history of malignancy in 1992 was found to be correlated with NH admission 4 years later (OR, 3.1; 95% CI, 1.1-9.1). History of malignancy was not associated with mortality. CONCLUSIONS: Cancer history had limited influence on healthcare use and mortality. Efforts aimed at improving health-related outcomes in older cancer survivors should continue to focus on attenuating the impact of comorbid conditions. (c) 2004 American Cancer Society
BACKGROUND: Older cancer survivors use healthcare services to an increased extent relative to their counterparts who have no history of malignant disease. In the current study, the authors set out to assess the effects of cancer history and comorbid conditions on healthcare use and mortality. METHODS: Using information from the 1992 North Carolina Established Populations for Epidemiologic Study of the Elderly database, study participants were classified as having no history of malignant disease or as having a recent (cancer diagnosed < 1 year earlier), intermediate (cancer diagnosed 1-6 years earlier), or remote (cancer diagnosed > 6 years earlier) history of malignancy. Overall, 15 different comorbid conditions were ascertained. Logistic regression models adjusted for sociodemographic factors, tobacco and alcohol use, and functional measures were used to determine the risk of emergency room, hospital, and nursing home (NH) admission in 1992 and also in 1996 according to history of malignancy and presence of comorbid conditions. Using data from the National Death Registry, a similar controlled analysis of 7-year mortality also was performed. RESULTS: There were 2567 participants in the current study (mean age, 79 years; range, 71-102 years); 69% of all participants were women, 55% were African American, and 14% reported having a history of malignancy. Participants with a history of malignancy had an average of 3 comorbid conditions, and differences across groups in terms of cardiovascular and lung disease incidence were noted. Controlled analyses revealed that recent cancer history (odds ratio [OR], 15.5; 95% confidence interval [CI], 7.0-34.2) and intermediate cancer history (OR, 2.1; 95% CI, 1.4-3.3) were associated with same-year hospital admission. In addition, having a recent history of malignancy in 1992 was found to be correlated with NH admission 4 years later (OR, 3.1; 95% CI, 1.1-9.1). History of malignancy was not associated with mortality. CONCLUSIONS:Cancer history had limited influence on healthcare use and mortality. Efforts aimed at improving health-related outcomes in older cancer survivors should continue to focus on attenuating the impact of comorbid conditions. (c) 2004 American Cancer Society
Authors: Paul Krebs; Elliot J Coups; Marc B Feinstein; Jack E Burkhalter; Richard M Steingart; Amy Logue; Bernard J Park; Jamie S Ostroff Journal: J Cancer Surviv Date: 2011-07-02 Impact factor: 4.442
Authors: Laura-Mae Baldwin; Sharon A Dobie; Yong Cai; Barry G Saver; Pamela K Green; C Y Wang Journal: J Am Board Fam Med Date: 2011 Jan-Feb Impact factor: 2.657
Authors: L V van de Poll-Franse; F Mols; A J J M Vingerhoets; A C Voogd; R M H Roumen; J W W Coebergh Journal: Support Care Cancer Date: 2006-01-10 Impact factor: 3.603
Authors: Aakash Chauhan; Michael G House; Henry A Pitt; Attila Nakeeb; Thomas J Howard; Nicholas J Zyromski; C Max Schmidt; Chad G Ball; Keith D Lillemoe Journal: HPB (Oxford) Date: 2010-12-07 Impact factor: 3.647
Authors: Jessica P Hwang; Holly M Holmes; Michael A Kallen; Joe Ensor; Jason Etchegaray; Rana Saab; Rebecca B Arbuckle; Krista M King; Carmen P Escalante Journal: Support Care Cancer Date: 2009-10-20 Impact factor: 3.603
Authors: Joanna Sulicka; Agnieszka Pac; Monika Puzianowska-Kuźnicka; Tomasz Zdrojewski; Jerzy Chudek; Beata Tobiasz-Adamczyk; Małgorzata Mossakowska; Anna Skalska; Andrzej Więcek; Tomasz Grodzicki Journal: J Cancer Surviv Date: 2018-01-09 Impact factor: 4.442