Literature DB >> 15469833

Untangling the web: mitochondrial fission and apoptosis.

Scott A Oakes1, Stanley J Korsmeyer.   

Abstract

Mitochondria exist as an interconnected network that is constantly remodeled by balancing membrane fission and fusion events. A new study by Szabadkai et al. in the October 8th issue of Molecular Cell shows that dynamin-related protein 1 (Drp1)-induced scission hinders the ability of mitochondria to transport calcium across the cell and mediate apoptosis.

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Year:  2004        PMID: 15469833     DOI: 10.1016/j.devcel.2004.09.010

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  4 in total

1.  The mitochondrial fission regulator DRP3B does not regulate cell death in plants.

Authors:  Keiko Yoshinaga; Masaru Fujimoto; Shin-Ichi Arimura; Nobuhiro Tsutsumi; Hirofumi Uchimiya; Maki Kawai-Yamada
Journal:  Ann Bot       Date:  2006-03-13       Impact factor: 4.357

2.  Amyloid β-42 induces neuronal apoptosis by targeting mitochondria.

Authors:  Xiao-Jian Han; Yang-Yang Hu; Zhang-Jian Yang; Li-Ping Jiang; Sheng-Lan Shi; Ye-Ru Li; Miao-Yu Guo; Hong-Li Wu; Yu-Ying Wan
Journal:  Mol Med Rep       Date:  2017-08-10       Impact factor: 2.952

3.  β-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma.

Authors:  E Pasquier; J Street; C Pouchy; M Carre; A J Gifford; J Murray; M D Norris; T Trahair; N Andre; M Kavallaris
Journal:  Br J Cancer       Date:  2013-05-21       Impact factor: 7.640

4.  CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology.

Authors:  Xiao-Jian Han; Yun-Fei Lu; Shun-Ai Li; Taku Kaitsuka; Yasufumi Sato; Kazuhito Tomizawa; Angus C Nairn; Kohji Takei; Hideki Matsui; Masayuki Matsushita
Journal:  J Cell Biol       Date:  2008-08-11       Impact factor: 10.539

  4 in total

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