Literature DB >> 15469224

New therapies in tendon reconstruction.

Michael J DeFranco1, Kathleen Derwin, Joseph P Iannotti.   

Abstract

Despite the use of various types of grafts, no surgical treatment currently exists to restore a tendon to its normal condition. Tissue engineering techniques are being used to develop therapies for tendon reconstruction. Biologic and synthetic scaffolds can both repair tendon defects and improve healing by allowing for the regeneration of the tendon's natural biologic composition to restore its mechanical capacity. This process can be further enhanced through augmentation methods such as cell seeding, growth factor implantation, and gene therapy.

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Year:  2004        PMID: 15469224     DOI: 10.5435/00124635-200409000-00004

Source DB:  PubMed          Journal:  J Am Acad Orthop Surg        ISSN: 1067-151X            Impact factor:   3.020


  8 in total

1.  Conversion of mechanical force into TGF-β-mediated biochemical signals.

Authors:  Toru Maeda; Tomoya Sakabe; Ataru Sunaga; Keiko Sakai; Alexander L Rivera; Douglas R Keene; Takako Sasaki; Edward Stavnezer; Joseph Iannotti; Ronen Schweitzer; Dusko Ilic; Harihara Baskaran; Takao Sakai
Journal:  Curr Biol       Date:  2011-05-19       Impact factor: 10.834

Review 2.  Musculoskeletal diseases--tendon.

Authors:  Tomoya Sakabe; Takao Sakai
Journal:  Br Med Bull       Date:  2011-07-04       Impact factor: 4.291

Review 3.  Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering.

Authors:  Christina W Cheng; Loran D Solorio; Eben Alsberg
Journal:  Biotechnol Adv       Date:  2014-01-10       Impact factor: 14.227

4.  Preliminary results after rotator cuff reconstruction augmented with an autologous periosteal flap.

Authors:  Markus Scheibel; Anna Brown; Klaus Woertler; Andreas B Imhoff
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2006-08-22       Impact factor: 4.342

5.  Improvement of tendon repair using muscle grafts transduced with TGF-β1 cDNA.

Authors:  Martin Majewski; Ryan M Porter; Oliver B Betz; Volker M Betz; Harald Clahsen; Rudolf Flückiger; Christopher H Evans
Journal:  Eur Cell Mater       Date:  2012-02-16       Impact factor: 3.942

6.  Novel treatment of a failed quadriceps tendon repair in a diabetic patient using a patella-quadriceps tendon allograft.

Authors:  Sasha C Druskin; Scott A Rodeo
Journal:  HSS J       Date:  2012-09-28

7.  Growth differentiation factor‑5 induces tenomodulin expression via phosphorylation of p38 and promotes viability of murine mesenchymal stem cells from compact bone.

Authors:  Yanlong Qu; Li Zhou; Bing Lv; Chunlei Wang; Pengwei Li
Journal:  Mol Med Rep       Date:  2017-12-20       Impact factor: 2.952

8.  Tissue specific characteristics of cells isolated from human and rat tendons and ligaments.

Authors:  N Scutt; C G Rolf; A Scutt
Journal:  J Orthop Surg Res       Date:  2008-07-24       Impact factor: 2.359

  8 in total

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