Literature DB >> 15468886

Evaluation of suitable biodegradable scaffolds for engineered bone tissue.

M Y Phang1, M H Angela Ng, K K Tan, B S Aminuddin, B H I Ruszymah, O Fauziah.   

Abstract

Tricalcium phosphate/hydroxyapatite (TCP/HA), hydroxyapatite (HA), chitosan and calcium sulphate (CaSO4) were studied and evaluated for possible bone tissue engineered construct acting as good support for osteogenic cells to proliferate, differentiate, and eventually spread and integrate into the scaffold. Surface morphology visualized by SEM showed that scaffold materials with additional fibrin had more cell densities attached than those without, depicting that the presence of fibrin and collagen fibers were truly a favourite choice of cells to attach. In comparison of various biomaterials used incorporated with fibrin, TCP/HA had the most cluster of cells attached.

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Year:  2004        PMID： 15468886

Source DB:  PubMed          Journal:  Med J Malaysia        ISSN： 0300-5283


  4 in total

1.  The effect of collagen I mimetic peptides on mesenchymal stem cell adhesion and differentiation, and on bone formation at hydroxyapatite surfaces.

Authors:  Kristin M Hennessy; Beth E Pollot; William C Clem; Matthew C Phipps; Amber A Sawyer; Bonnie K Culpepper; Susan L Bellis
Journal:  Biomaterials       Date:  2009-01-20       Impact factor: 12.479

2.  Tricalcium phosphate/hydroxyapatite (TCP-HA) bone scaffold as potential candidate for the formation of tissue engineered bone.

Authors:  Shamsul Bin Sulaiman; Tan Kok Keong; Chen Hui Cheng; Aminuddin Bin Saim; Ruszymah Bt Hj Idrus
Journal:  Indian J Med Res       Date:  2013-06       Impact factor: 2.375

3.  Customized Design 3D Printed PLGA/Calcium Sulfate Scaffold Enhances Mechanical and Biological Properties for Bone Regeneration.

Authors:  Tao Liu; Zhan Li; Li Zhao; Zehua Chen; Zefeng Lin; Binglin Li; Zhibin Feng; Panshi Jin; Jinwei Zhang; Zugui Wu; Huai Wu; Xuemeng Xu; Xiangling Ye; Ying Zhang
Journal:  Front Bioeng Biotechnol       Date:  2022-06-23

4.  Repair of segmental load-bearing bone defect by autologous mesenchymal stem cells and plasma-derived fibrin impregnated ceramic block results in early recovery of limb function.

Authors:  Min Hwei Ng; Suryasmi Duski; Kok Keong Tan; Mohd Reusmaazran Yusof; Kiat Cheong Low; Isa Mohamed Rose; Zahiah Mohamed; Aminuddin Bin Saim; Ruszymah Bt Hj Idrus
Journal:  Biomed Res Int       Date:  2014-07-08       Impact factor: 3.411
  4 in total

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