| Literature DB >> 15468792 |
K H Chua1, B S Aminuddin, N H Fuzina, B H I Ruszymah.
Abstract
The regulation roles of insulin-like growth factor-1 (IGF-1) with basic fibroblast growth factor (bFGF) and transforming growth factor beta 2 (TGFbeta2) in human nasal septum chondrocytes monolayer culture and cartilage engineering was investigated in this study. The role of IGF-1 with bFGF and TGFbeta2 was investigated by measuring chondrocyte growth kinetic and collagen genes expression. IGF-1 together with bFGF and TGFbeta2 promote cartilage tissue engineering, increase type II collagen expression and enhance the histological features of engineered cartilage.Entities:
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Year: 2004 PMID: 15468792
Source DB: PubMed Journal: Med J Malaysia ISSN: 0300-5283