Literature DB >> 15468600

Encapsulated, genetically modified cells producing in vivo therapeutics.

Oliver Hauser1, Eva Prieschl-Grassauer, Brian Salmons.   

Abstract

The ability to implant genetically modified cells in immuno-isolating materials has much potential for therapeutic use. This review presents the different types of polymer that can be used for encapsulation of cells and the recent use of genetically modified, encapsulated and thus immunoprotected cells for the treatment of diseases in animal models and clinical trials. Some of the challenges faced by these technologies and potential solutions are also discussed.

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Year:  2004        PMID: 15468600

Source DB:  PubMed          Journal:  Curr Opin Mol Ther        ISSN: 1464-8431


  3 in total

1.  Insulin-producing cells from tissue stem/progenitor cells: are autologous cells preferable to allogeneic?

Authors:  Shimon Efrat
Journal:  Rev Diabet Stud       Date:  2005-05-10

Review 2.  Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies.

Authors:  Detlev Boison
Journal:  Epilepsy Res       Date:  2009-05-09       Impact factor: 3.045

3.  Magnetic field-controlled gene expression in encapsulated cells.

Authors:  Viktoria Ortner; Cornelius Kaspar; Christian Halter; Lars Töllner; Olga Mykhaylyk; Johann Walzer; Walter H Günzburg; John A Dangerfield; Christine Hohenadl; Thomas Czerny
Journal:  J Control Release       Date:  2011-12-16       Impact factor: 9.776

  3 in total

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