Literature DB >> 15467827

Judging a virus by its cover.

Eva Szomolanyi-Tsuda1, Raymond M Welsh.   

Abstract

The production of protective neutralizing antibodies occurs quickly in some viral infections but very slowly in others. In a new study, surface glycoproteins (the targets of neutralization) of 2 different viruses were genetically switched. Analysis of the neutralizing antibody response to each of the 2 parent and recombinant viruses in infected mice revealed that the speed of neutralizing antibody induction was intrinsically dependent on the surface glycoprotein and not the rest of the virus.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15467827      PMCID： PMC518670          DOI： 10.1172/JCI23098

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  19 in total

1.  Correlation of T cell independence of antibody responses with antigen dose reaching secondary lymphoid organs: implications for splenectomized patients and vaccine design.

Authors:  A F Ochsenbein; D D Pinschewer; B Odermatt; A Ciurea; H Hengartner; R M Zinkernagel
Journal:  J Immunol       Date:  2000-06-15       Impact factor: 5.422

2.  A role for carbohydrates in immune evasion in AIDS.

Authors:  J N Reitter; R E Means; R C Desrosiers
Journal:  Nat Med       Date:  1998-06       Impact factor: 53.440

3.  T-Cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus-like particles.

Authors:  E Szomolanyi-Tsuda; Q P Le; R L Garcea; R M Welsh
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

Review 4.  Neutralizing antiviral B cell responses.

Authors:  M F Bachmann; R M Zinkernagel
Journal:  Annu Rev Immunol       Date:  1997       Impact factor: 28.527

5.  The role of antibody concentration and avidity in antiviral protection.

Authors:  M F Bachmann; U Kalinke; A Althage; G Freer; C Burkhart; H Roost; M Aguet; H Hengartner; R M Zinkernagel
Journal:  Science       Date:  1997-06-27       Impact factor: 47.728

Review 6.  Immunity to rotavirus infection in mice.

Authors:  M A Franco; H B Greenberg
Journal:  J Infect Dis       Date:  1999-05       Impact factor: 5.226

Review 7.  Impact of yellow fever on the developing world.

Authors:  O Tomori
Journal:  Adv Virus Res       Date:  1999       Impact factor: 9.937

Review 8.  Role of the B-cell response in recovery of mice from primary influenza virus infection.

Authors:  W Gerhard; K Mozdzanowska; M Furchner; G Washko; K Maiese
Journal:  Immunol Rev       Date:  1997-10       Impact factor: 12.988

9.  Th cell-deficient mice control influenza virus infection more effectively than Th- and B cell-deficient mice: evidence for a Th-independent contribution by B cells to virus clearance.

Authors:  K Mozdzanowska; K Maiese; W Gerhard
Journal:  J Immunol       Date:  2000-03-01       Impact factor: 5.422

10.  The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

Authors:  U Kalinke; E M Bucher; B Ernst; A Oxenius; H P Roost; S Geley; R Kofler; R M Zinkernagel; H Hengartner
Journal:  Immunity       Date:  1996-12       Impact factor: 31.745
View more
  1 in total

Review 1.  The gastrointestinal frontier: IgA and viruses.

Authors:  Sarah E Blutt; Margaret E Conner
Journal:  Front Immunol       Date:  2013-11-28       Impact factor: 7.561
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.