Literature DB >> 15467774

Changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women.

K He1, F B Hu, G A Colditz, J E Manson, W C Willett, S Liu.   

Abstract

OBJECTIVE: To examine the changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women.
DESIGN: Prospective cohort study with 12 y of follow-up conducted in the Nurses' Health Study.
SUBJECTS: A total of 74,063 female nurses aged 38-63 y, who were free of cardiovascular disease, cancer, and diabetes at baseline in 1984. MEASUREMENTS: Dietary information was collected using a validated food frequency questionnaire, and body weight and height were self-reported.
RESULTS: During the 12-y follow-up, participants tended to gain weight with aging, but those with the largest increase in fruit and vegetable intake had a 24% of lower risk of becoming obese (BMI> or =30 kg/m2) compared with those who had the largest decrease in intake after adjustment for age, physical activity, smoking, total energy intake, and other lifestyle variables (relative risk (RR), 0.76; 95% confidence interval (CI), 0.69-0.86; P for trend <0.0001). For major weight gain (> or =25 kg), women with the largest increase in intake of fruits and vegetables had a 28% lower risk compared to those in the other extreme group (RR, 0.72; 95% CI, 0.55-0.93; P=0.01). Similar results were observed for changes in intake of fruits and vegetables when analyzed separately.
CONCLUSIONS: Our findings suggest that increasing intake of fruits and vegetables may reduce long-term risk of obesity and weight gain among middle-aged women.

Entities:  

Mesh:

Year:  2004        PMID: 15467774     DOI: 10.1038/sj.ijo.0802795

Source DB:  PubMed          Journal:  Int J Obes Relat Metab Disord


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