OBJECTIVE: To evaluate children with obstructive sleep apnea syndrome (OSAS) for features of attention deficit disorder (ADD) using an objective test of inattention and impulsivity: Test of Variables of Attention (TOVA) and then to determine whether tonsillectomy and adenoidectomy (T+A) results in an improvement in TOVA scores. STUDY DESIGN AND SETTING: This study was a prospective interventional comparative trial in a tertiary care children's hospital. Nineteen children ages 5 to 14 years with OSAS, and otherwise healthy, with a clinical indication for T+A. Preoperative and 2 months postoperative OSA-18, CBCL questionnaires, and TOVA scores were evaluated. RESULTS: The preoperative TOVA scores were in the abnormal range in 12/19 (63%) of the children. The mean preoperative TOVA score was -2.9 (+/- 3.1). The mean postoperative TOVA score was -0.4 (+/-2.8). The improvement in the TOVA scores was significant ( P < 0.0001, t -test). CONCLUSION: This preliminary data suggests that treatment of OSAS with T+A results in significant improvement in objective parameters of inattention and impulsivity. Significance These findings may be important in understanding the impact of OSAS and therapeutic interventions on behavioral problems in children.
OBJECTIVE: To evaluate children with obstructive sleep apnea syndrome (OSAS) for features of attention deficit disorder (ADD) using an objective test of inattention and impulsivity: Test of Variables of Attention (TOVA) and then to determine whether tonsillectomy and adenoidectomy (T+A) results in an improvement in TOVA scores. STUDY DESIGN AND SETTING: This study was a prospective interventional comparative trial in a tertiary care children's hospital. Nineteen children ages 5 to 14 years with OSAS, and otherwise healthy, with a clinical indication for T+A. Preoperative and 2 months postoperative OSA-18, CBCL questionnaires, and TOVA scores were evaluated. RESULTS: The preoperative TOVA scores were in the abnormal range in 12/19 (63%) of the children. The mean preoperative TOVA score was -2.9 (+/- 3.1). The mean postoperative TOVA score was -0.4 (+/-2.8). The improvement in the TOVA scores was significant ( P < 0.0001, t -test). CONCLUSION: This preliminary data suggests that treatment of OSAS with T+A results in significant improvement in objective parameters of inattention and impulsivity. Significance These findings may be important in understanding the impact of OSAS and therapeutic interventions on behavioral problems in children.
Authors: H Gerry Taylor; Susan R Bowen; Dean W Beebe; Elise Hodges; Raouf Amin; Raanan Arens; Ronald D Chervin; Susan L Garetz; Eliot S Katz; Reneé H Moore; Knashawn H Morales; Hiren Muzumdar; Shalini Paruthi; Carol L Rosen; Anjali Sadhwani; Nina Hattiangadi Thomas; Janice Ware; Carole L Marcus; Susan S Ellenberg; Susan Redline; Bruno Giordani Journal: Pediatrics Date: 2016-08 Impact factor: 7.124
Authors: Bruno Giordani; Elise K Hodges; Kenneth E Guire; Deborah L Ruzicka; James E Dillon; Robert A Weatherly; Susan L Garetz; Ronald D Chervin Journal: J Int Neuropsychol Soc Date: 2008-07 Impact factor: 2.892
Authors: Arthur S Walters; Rosalia Silvestri; Marco Zucconi; Ranju Chandrashekariah; Eric Konofal Journal: J Clin Sleep Med Date: 2008-12-15 Impact factor: 4.062
Authors: James E Dillon; Sarah Blunden; Deborah L Ruzicka; Kenneth E Guire; Donna Champine; Robert A Weatherly; Elise K Hodges; Bruno J Giordani; Ronald D Chervin Journal: J Am Acad Child Adolesc Psychiatry Date: 2007-11 Impact factor: 8.829
Authors: Mark J Kohler; Kurt Lushington; Cameron J van den Heuvel; James Martin; Yvonne Pamula; Declan Kennedy Journal: PLoS One Date: 2009-10-06 Impact factor: 3.240