| Literature DB >> 15466055 |
Caroline E Cameron1, Elizabeth L Brown, Janelle M Y Kuroiwa, Lynn M Schnapp, Nathan L Brouwer.
Abstract
Putative adhesins were predicted by computer analysis of the Treponema pallidum genome. Two treponemal proteins, Tp0155 and Tp0483, demonstrated specific attachment to fibronectin, blocked bacterial adherence to fibronectin-coated slides, and supported attachment of fibronectin-producing mammalian cells. These results suggest Tp0155 and Tp0483 are fibronectin-binding proteins mediating T. pallidum-host interactions.Entities:
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Year: 2004 PMID: 15466055 PMCID: PMC522185 DOI: 10.1128/JB.186.20.7019-7022.2004
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490