OBJECTIVE: To evaluate whether hyperglycaemia in the first 48 h after infrainguinal vascular surgery is a risk factor for post-operative infection, independent from factors associated with insulin resistance and surgical stress. DESIGN: Retrospective cohort study. PATIENTS AND METHODS: Patients who underwent infrainguinal vascular surgery in our hospital between March 1998 and March 2003 were included. Glucose values until 48 h after surgery were retrieved from laboratory reports. Post-operative infections, treated with antibiotics, during hospital stay were scored until 30 days after surgery. Data were analysed with univariate and multivariate logistic regression analyses. RESULTS: At least one post-operative glucose value was retrieved for 211/275 (77%) patients. The incidence of post-operative infections was 84/275 (31%). When corrected for factors associated with insulin resistance and surgical stress, post-operative glucose levels were found to be an independent risk factor for post-operative infections (odds ratio top quartile versus lowest quartile: 5.1; 95% confidence interval: 1.6-17.1; P=0.007). CONCLUSION: Post-operative glucose levels appear to be an independent risk factor for infections after infrainguinal vascular surgery. This finding requires confirmation in a prospective study.
OBJECTIVE: To evaluate whether hyperglycaemia in the first 48 h after infrainguinal vascular surgery is a risk factor for post-operative infection, independent from factors associated with insulin resistance and surgical stress. DESIGN: Retrospective cohort study. PATIENTS AND METHODS: Patients who underwent infrainguinal vascular surgery in our hospital between March 1998 and March 2003 were included. Glucose values until 48 h after surgery were retrieved from laboratory reports. Post-operative infections, treated with antibiotics, during hospital stay were scored until 30 days after surgery. Data were analysed with univariate and multivariate logistic regression analyses. RESULTS: At least one post-operative glucose value was retrieved for 211/275 (77%) patients. The incidence of post-operative infections was 84/275 (31%). When corrected for factors associated with insulin resistance and surgical stress, post-operative glucose levels were found to be an independent risk factor for post-operative infections (odds ratio top quartile versus lowest quartile: 5.1; 95% confidence interval: 1.6-17.1; P=0.007). CONCLUSION: Post-operative glucose levels appear to be an independent risk factor for infections after infrainguinal vascular surgery. This finding requires confirmation in a prospective study.
Authors: Rebecca L Smith; John C Lin; P David Adelson; Patrick M Kochanek; Ericka L Fink; Stephen R Wisniewski; Hülya Bayir; Elizabeth C Tyler-Kabara; Robert S B Clark; S Danielle Brown; Michael J Bell Journal: Pediatr Crit Care Med Date: 2012-01 Impact factor: 3.624
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Authors: Edmund B Chen; Michael J Nooromid; Irene B Helenowski; Nathaniel J Soper; Amy L Halverson Journal: Surgery Date: 2019-07-24 Impact factor: 3.982
Authors: Duncan Macrae; John Pappachan; Richard Grieve; Roger Parslow; Simon Nadel; Margrid Schindler; Paul Baines; Peter-Marc Fortune; Zdenek Slavik; Allan Goldman; Ann Truesdale; Helen Betts; Elizabeth Allen; Claire Snowdon; Deborah Percy; Michael Broadhead; Tara Quick; Mark Peters; Kevin Morris; Robert Tasker; Diana Elbourne Journal: BMC Pediatr Date: 2010-02-05 Impact factor: 2.125