A Jamal1, R Kalantari. 1. OB/GYN Department, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. af_jamal@yahoo.com
Abstract
OBJECTIVE: To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. METHOD: Two hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either a low dose protocol (1.5 microm/min initially, increased by 1.5 microm/min every 30 min) or a high dose protocol (4.5 microm/min initially, increased by 4.5 microm/min every 30 min). RESULTS: High dose of oxytocin was associated with a significant shortening of labor 4 (1.10-10) vs. 6 (1-10) h, p<0.0001 without a significant difference in cesarean delivery rate, neonatal and maternal outcome. CONCLUSION: The use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.
RCT Entities:
OBJECTIVE: To compare the efficacy and safety of high dose oxytocin in the augmentation of labor. METHOD: Two hundred pregnant women requiring augmentation of labor were randomly assigned to receive oxytocin by either a low dose protocol (1.5 microm/min initially, increased by 1.5 microm/min every 30 min) or a high dose protocol (4.5 microm/min initially, increased by 4.5 microm/min every 30 min). RESULTS: High dose of oxytocin was associated with a significant shortening of labor 4 (1.10-10) vs. 6 (1-10) h, p<0.0001 without a significant difference in cesarean delivery rate, neonatal and maternal outcome. CONCLUSION: The use of high dose oxytocin is associated with significantly shorter labor without any adverse fetal and maternal effects.
Authors: Fedyeh Haghollahi; Soghra Khazardoost; Sedigheh Hantoushzadeh; Mohammad Mehdi Naghizadeh; Batool Rashidi Journal: J Family Reprod Health Date: 2014-06