Literature DB >> 15464403

What, if anything, is the medial temporal lobe, and how can the amygdala be part of it if there is no such thing?

Elisabeth A Murray1, Steven P Wise.   

Abstract

Should the medial temporal lobe (MTL) of primates--which includes allocortical structures such as the hippocampus, neocortical structures such as the parahippocampal cortex, and nuclear structures such as the basolateral amygdala--be considered a single "thing"? According to the prevailing view, here termed the reification theory, the answer is yes. According to this theory, the MTL functions as an amalgamated entity that provides the neuronal mechanisms for declarative memory; the greater the damage to the MTL or any of its components, the greater the deleterious effects on declarative memory. A countervailing view, here called the balkanization theory, holds that the various components of the MTL process and store different kinds of information. According to this theory, damage to each part of the MTL causes a unique set of behavioral deficits-some involving memory, others involving perception, and yet others involving response selection. The empirical neuropsychological evidence favors the balkanization theory, as do some new concepts in theoretical neuroanatomy.

Mesh:

Year:  2004        PMID: 15464403     DOI: 10.1016/j.nlm.2004.05.005

Source DB:  PubMed          Journal:  Neurobiol Learn Mem        ISSN: 1074-7427            Impact factor:   2.877


  7 in total

1.  Striatal and medial temporal lobe functional interactions during visuomotor associative learning.

Authors:  Aaron T Mattfeld; Craig E L Stark
Journal:  Cereb Cortex       Date:  2010-08-05       Impact factor: 5.357

2.  Why is there a special issue on perirhinal cortex in a journal called hippocampus? The perirhinal cortex in historical perspective.

Authors:  Elisabeth A Murray; Steven P Wise
Journal:  Hippocampus       Date:  2012-10       Impact factor: 3.899

3.  5-HT1A receptor expression during memory formation.

Authors:  H Luna-Munguía; L Manuel-Apolinar; L Rocha; A Meneses
Journal:  Psychopharmacology (Berl)       Date:  2005-10-14       Impact factor: 4.530

4.  Δ⁹Tetrahydrocannabinol impairs visuo-spatial associative learning and spatial working memory in rhesus macaques.

Authors:  Michael A Taffe
Journal:  J Psychopharmacol       Date:  2012-04-22       Impact factor: 4.153

5.  Recognition Memory is Associated with Distinct Patterns of Regional Gray Matter Volumes in Young and Aged Monkeys.

Authors:  C'iana P Cooper; Andrea T Shafer; Nicole M Armstrong; Sharyn L Rossi; Jennifer Young; Christa Herold; Hong Gu; Yihong Yang; Elliot A Stein; Susan M Resnick; Peter R Rapp
Journal:  Cereb Cortex       Date:  2022-02-19       Impact factor: 4.861

6.  What, if anything, can monkeys tell us about human amnesia when they can't say anything at all?

Authors:  Elisabeth A Murray; Steven P Wise
Journal:  Neuropsychologia       Date:  2010-01-25       Impact factor: 3.139

Review 7.  Angst and the amygdala.

Authors:  Jay Schulkin
Journal:  Dialogues Clin Neurosci       Date:  2006       Impact factor: 5.986

  7 in total

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