Literature DB >> 15464378

Production technologies for monoclonal antibodies and their fragments.

Dana C Andersen1, Dorothea E Reilly.   

Abstract

In recent years, monoclonal antibodies have emerged as an increasingly important class of human therapeutics. A variety of forms of antibodies, including fragments such as Fabs, Fab'2s and single-chain Fvs, are also being evaluated for a range of different purposes. A variety of expression systems and improvements within these systems have been developed to address these growing and diverse needs.

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Year:  2004        PMID: 15464378     DOI: 10.1016/j.copbio.2004.08.002

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  28 in total

1.  Development of a novel mammalian cell surface antibody display platform.

Authors:  Chen Zhou; Frederick W Jacobsen; Ling Cai; Qing Chen; Weyen David Shen
Journal:  MAbs       Date:  2010-09-01       Impact factor: 5.857

Review 2.  Clinical pharmacokinetics of therapeutic monoclonal antibodies.

Authors:  Ron J Keizer; Alwin D R Huitema; Jan H M Schellens; Jos H Beijnen
Journal:  Clin Pharmacokinet       Date:  2010-08       Impact factor: 6.447

Review 3.  Cell culture processes for monoclonal antibody production.

Authors:  Feng Li; Natarajan Vijayasankaran; Amy Yijuan Shen; Robert Kiss; Ashraf Amanullah
Journal:  MAbs       Date:  2010-09-01       Impact factor: 5.857

4.  Production and characterization of monoclonal antibodies sensitive to conformation in the 5HT2c serotonin receptor.

Authors:  Filippo Mancia; Susan Brenner-Morton; Risa Siegel; Zahra Assur; Yonghua Sun; Ira Schieren; Monica Mendelsohn; Richard Axel; Wayne A Hendrickson
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-06       Impact factor: 11.205

5.  Aglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system.

Authors:  Gang Yin; Eudean D Garces; Junhao Yang; Juan Zhang; Cuong Tran; Alexander R Steiner; Christine Roos; Sunil Bajad; Susan Hudak; Kalyani Penta; James Zawada; Sonia Pollitt; Christopher J Murray
Journal:  MAbs       Date:  2012-03-01       Impact factor: 5.857

6.  An efficient route to bispecific antibody production using single-reactor mammalian co-culture.

Authors:  Whitney Shatz; Domingos Ng; George Dutina; Athena W Wong; Diana Ronai Dunshee; Junichiro Sonoda; Amy Shen; Justin M Scheer
Journal:  MAbs       Date:  2016 Nov/Dec       Impact factor: 5.857

Review 7.  Gene expression in Mammalian cells and its applications.

Authors:  Kishwar Hayat Khan
Journal:  Adv Pharm Bull       Date:  2013-08-20

8.  Comprehensive engineering of Escherichia coli for enhanced expression of IgG antibodies.

Authors:  Tomohiro Makino; Georgios Skretas; Tae-Hyun Kang; George Georgiou
Journal:  Metab Eng       Date:  2010-12-03       Impact factor: 9.783

Review 9.  With or without sugar? (A)glycosylation of therapeutic antibodies.

Authors:  Dmitrij Hristodorov; Rainer Fischer; Lars Linden
Journal:  Mol Biotechnol       Date:  2013-07       Impact factor: 2.695

10.  Genetic modification of mesenchymal stem cells to express a single-chain antibody against EGFRvIII on the cell surface.

Authors:  Irina V Balyasnikova; Rosa Franco-Gou; J Michael Mathis; Maciej S Lesniak
Journal:  J Tissue Eng Regen Med       Date:  2010-06       Impact factor: 3.963

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