| Literature DB >> 15464261 |
Whitney Evans1, Hon Chung Fung, John Steele, Johanna Eerola, Pentti Tienari, Alan Pittman, Rohan de Silva, Amanda Myers, Fabienne Wavrant-De Vrieze, Andrew Singleton, John Hardy.
Abstract
We have assessed the distribution of the tau H1/H2 haplotype in the publicly available reference series of samples with representatives of most racial groups. This analysis shows that the H2 haplotype is probably exclusively Caucasian in origin and its marginal occurrence in other racial groups is likely to reflect admixture. We discuss this observation in terms of the origin of the H2 haplotype and the epidemiology of the tauopathies.Entities:
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Year: 2004 PMID： 15464261 DOI： 10.1016/j.neulet.2004.05.119
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046