| Literature DB >> 15463932 |
Carlos M Farinha1, Deborah Penque, Mónica Roxo-Rosa, Gergely Lukacs, Robert Dormer, Margaret McPherson, Malcolm Pereira, Alice G M Bot, Huub Jorna, Rob Willemsen, Hugo Dejonge, Ghanshyam D Heda, Christopher R Marino, Pascale Fanen, Alexandre Hinzpeter, Joanna Lipecka, Janine Fritsch, Martina Gentzsch, Aleksander Edelman, Margarida D Amaral.
Abstract
Detection of cystic fibrosis transmembrane conductance regulator (CFTR) protein is usually a difficult task to accomplish due to the low levels of expression and high turnover that this membrane protein is submitted to in the cell. Common biochemical methods can be used for the detection of CFTR but several critical points must be taken into account. The scope of this article is to outline biochemical methods commonly used to assess CFTR expression, processing and membrane localization.Entities:
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Year: 2004 PMID： 15463932 DOI： 10.1016/j.jcf.2004.05.017
Source DB: PubMed Journal: J Cyst Fibros ISSN： 1569-1993 Impact factor: 5.482