Literature DB >> 15463931

Antibodies for CFTR studies.

Filipa Mendes1, Carlos M Farinha, Mónica Roxo-Rosa, Pascale Fanen, Aleksander Edelman, Robert Dormer, Margaret McPherson, Heather Davidson, Edith Puchelle, Hugo De Jonge, Ghanshyam D Heda, Martina Gentzsch, Gergely Lukacs, Deborah Penque, Margarida D Amaral.   

Abstract

For most expression studies focusing on the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, sensitive and specific antibodies (Abs) are critically needed. Several Abs have been produced commercially or by research laboratories for CFTR detection in both cell lines with heterologous or endogenous expression and native cells/tissues. Here, we review the applicability of most Abs currently in use in CF research for the biochemical and/or immunocytochemical detection of CFTR.

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Year:  2004        PMID: 15463931     DOI: 10.1016/j.jcf.2004.05.016

Source DB:  PubMed          Journal:  J Cyst Fibros        ISSN: 1569-1993            Impact factor:   5.482


  13 in total

Review 1.  Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.

Authors:  Margarida D Amaral
Journal:  J Inherit Metab Dis       Date:  2006 Apr-Jun       Impact factor: 4.982

2.  Ion transport mechanisms linked to bicarbonate secretion in the esophageal submucosal glands.

Authors:  Solange Abdulnour-Nakhoul; Hani N Nakhoul; Medhat I Kalliny; Alex Gyftopoulos; Edd Rabon; Rienk Doetjes; Karen Brown; Nazih L Nakhoul
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-04-06       Impact factor: 3.619

3.  The cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in maturation stage ameloblasts, odontoblasts and bone cells.

Authors:  Antonius Bronckers; Lida Kalogeraki; Huub J N Jorna; Martina Wilke; Theodore J Bervoets; Donacian M Lyaruu; Behrouz Zandieh-Doulabi; Pamela Denbesten; Hugo de Jonge
Journal:  Bone       Date:  2009-12-30       Impact factor: 4.398

Review 4.  Detection of cystic fibrosis transmembrane conductance regulator activity in early-phase clinical trials.

Authors:  Steven M Rowe; Frank Accurso; John P Clancy
Journal:  Proc Am Thorac Soc       Date:  2007-08-01

5.  Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in human bone.

Authors:  Elizabeth F Shead; Charles S Haworth; Alison M Condliffe; Damian J McKeon; Mike A Scott; Juliet E Compston
Journal:  Thorax       Date:  2007-07       Impact factor: 9.139

Review 6.  On the Corner of Models and Cure: Gene Editing in Cystic Fibrosis.

Authors:  Marjolein Ensinck; Angélique Mottais; Claire Detry; Teresinha Leal; Marianne S Carlon
Journal:  Front Pharmacol       Date:  2021-04-27       Impact factor: 5.810

7.  Binding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway.

Authors:  Céline René; Magali Taulan; Florence Iral; Julien Doudement; Aurore L'Honoré; Catherine Gerbon; Jacques Demaille; Mireille Claustres; Marie-Catherine Romey
Journal:  Nucleic Acids Res       Date:  2005-09-16       Impact factor: 16.971

8.  Correction of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis mice.

Authors:  Barbara Dhooghe; Sabrina Noël; Caroline Bouzin; Gaëtane Behets-Wydemans; Teresinha Leal
Journal:  PLoS One       Date:  2013-10-24       Impact factor: 3.240

9.  Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility.

Authors:  Maria F Servidoni; Marisa Sousa; Adriana M Vinagre; Silvia R Cardoso; Maria A Ribeiro; Luciana R Meirelles; Rita B de Carvalho; Karl Kunzelmann; Antônio F Ribeiro; José D Ribeiro; Margarida D Amaral
Journal:  BMC Gastroenterol       Date:  2013-05-20       Impact factor: 3.067

10.  In vitro prediction of stop-codon suppression by intravenous gentamicin in patients with cystic fibrosis: a pilot study.

Authors:  Isabelle Sermet-Gaudelus; Michel Renouil; Anne Fajac; Laure Bidou; Bastien Parbaille; Sébastien Pierrot; Nolwen Davy; Elise Bismuth; Philippe Reinert; Gérard Lenoir; Jean François Lesure; Jean Pierre Rousset; Aleksander Edelman
Journal:  BMC Med       Date:  2007-03-29       Impact factor: 8.775

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