| Literature DB >> 15463689 |
S Higgs1, A M Powers, K E Olson.
Abstract
In this review, Steve Higgs, Ann Powers and Ken Olson describe how alphavirus expression systems, based on infectious cDNA clones of Sindbis virus, constitute a novel RNA virus delivery system suitable for the efficient expression of heterologous gene products or RNA sequences in mosquito cells or adult mosquitoes. The technique permits ready assessment of molecular genetic-based methods of intracellular interference to infection and provides a powerful new tool for molecular biological studies in arthropods.Entities:
Year: 1993 PMID: 15463689 DOI: 10.1016/0169-4758(93)90098-z
Source DB: PubMed Journal: Parasitol Today ISSN: 0169-4758